Alcalá Ana C, Hidalgo Mayra A, Obando César, Vizzi Esmeralda, Liprandi Ferdinando, Ludert Juan E
Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Cientificas (IVIC), Caracas, Venezuela.
Acta Cient Venez. 2003;54(2):148-52.
Caliciviruses are a well-established cause of respiratory, vesicular and hemorrhagic diseases in animals. In addition, these viruses are an important cause of enteric diseases in humans. Recently, molecular analysis of several bovine enteric calicivirus isolates indicated that they are genetically close to human enteric calicivirus. To investigate if bovine enteric caliciviruses circulate in Venezuela, 129 stool samples collected between 1994 and 2000 were assayed by reverse transcription-polymerase chain reaction amplification. The presence of calicivirus was confirmed in one of the samples analyzed, collected in the Lara State from a healthy calf, 2 months old. Phylogenetic studies based on partial RNA polymerase sequences indicated that the Venezuelan isolate (Bo/NV/Lara/2000/VE) is most closely related to the genogroup III, genus Noroviruses.
杯状病毒是动物呼吸道、水疱性和出血性疾病的既定病因。此外，这些病毒是人类肠道疾病的重要病因。最近，对几种牛肠道杯状病毒分离株的分子分析表明，它们在基因上与人类肠道杯状病毒相近。为调查牛肠道杯状病毒是否在委内瑞拉传播，对1994年至2000年间收集的129份粪便样本进行了逆转录-聚合酶链反应扩增检测。在分析的其中一份样本中证实存在杯状病毒，该样本于2000年从拉腊州一头2个月大的健康小牛采集。基于部分RNA聚合酶序列的系统发育研究表明，委内瑞拉分离株（Bo/NV/Lara/2000/VE）与诺如病毒属基因组III关系最为密切。
