Li Jun, Li Shao-dan, Du Ning
302 Hospital of PLA, Beijing 100039.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Jan;24(1):28-31.
To summarize the clinical characteristics of severe acute respiratory syndrome (SARS) and observe the therapeutic effect with integrative Chinese and western medicine (ICWM) approach in treating patients with SARS.
Forty-eight patients selected from the authors' hospital, whose diagnosis confirmed as SARS were analysed to sum-up the diagnostic type and basic feature of patients and the chief clinical characteristics. All the patients were randomly divided into the trial group and the control group, 24 in each. The control group was treated with the western medical therapeutic program and the trial group was treated with ICWM therapeutic program. The differences between the two groups were compared in terms of development of illness, time of using corticosteroid and absorption time of pulmonary inflammatory lesion, etc.
Most patients were youth and adult aged between 18 to 40 years old, the initial symptom was mainly the high fever, accompanied with general soreness, chest stuffiness and cough, etc. The hospitalization time, body temperature fluctuation sustaining time and time of using corticosteroid in the trial group were shorter than those in the control group, showing significant difference (P < 0.05). ICWM treatment showed a better effect in defervescence and inflammatory lesion absorption time, but with no statistical significance.
Patients of SARS are mainly youth and adults in the prime of life, fever always appears as the initiation of illness and some accompanying symptoms would appear. As compared with the western treatment, ICWM treatment could evidently shorten the course of illness, prevent the rebounding of fever and reduce the time of using corticosteroid.
总结严重急性呼吸综合征(SARS)的临床特征,观察中西医结合疗法治疗SARS患者的疗效。
对作者所在医院选取的48例确诊为SARS的患者进行分析,总结患者的诊断类型、基本特征及主要临床特点。将所有患者随机分为试验组和对照组,每组24例。对照组采用西医治疗方案,试验组采用中西医结合治疗方案。比较两组在病情发展、使用糖皮质激素时间及肺部炎症病变吸收时间等方面的差异。
多数患者为18至40岁的青年及成年人,首发症状主要为高热,伴有全身酸痛、胸闷、咳嗽等。试验组的住院时间、体温波动持续时间及使用糖皮质激素时间均短于对照组,差异有统计学意义(P<0.05)。中西医结合治疗在退热及炎症病变吸收时间方面效果较好,但无统计学意义。
SARS患者以青壮年为主,发热常为起病初期表现,并伴有一些伴随症状。与西医治疗相比,中西医结合治疗能明显缩短病程,防止发热反弹,减少糖皮质激素使用时间。