Nishi Hiroyuki, Miyamoto Satoru, Minamimura Hirokazu, Ishikawa Takumi, Kato Yasuyuki, Arimoto Hideki, Ohue Kensuke, Shimizu Yoshihiro
Department of Cardiovascular Surgery, Osaka General City Hospital, Osaka, Japan.
Asian Cardiovasc Thorac Ann. 2004 Mar;12(1):69-74. doi: 10.1177/021849230401200117.
We sought to evaluate the safety and usefulness of deep hypothermic cardiopulmonary bypass with intervals of circulatory arrest for extensive thoracoabdominal aortic aneurysms. Between March 1994 and December 2002, 17 patients with Crawford type I and II were reviewed retrospectively. The patients were divided into two groups: group H (hypothermic circulatory arrest, n = 8) and group N (normothermic cardiopulmonary bypass, n = 9). In group H, in-hospital mortality was 12.5%, and that in group N was 11.1%. Operation times were similar between the two groups though the cardiopulmonary bypass time was significantly shorter in group N than in group H (p < 0.05). Postoperative paraplegia occurred in 1 patient of group N. Postoperative renal dysfunction occurred in none of group H except in 1 preoperative dialysis case, whilst it occurred in 6 patients of group N. Postoperative creatinine levels were significantly higher in group N than in group H. Three cases in group H required tracheostomy. Our experience with hypothermic cardiopulmonary bypass and circulatory arrest for diffuse type thoracoabdominal aortic aneurysm confirms the safety and efficacy of this technique. Although respiratory complications remain a problem, the technique is considered to be effective for renal protection.
我们旨在评估用于广泛胸腹主动脉瘤的深低温体外循环及循环阻断间隔的安全性和实用性。回顾性分析了1994年3月至2002年12月期间17例Crawford I型和II型患者。患者分为两组:H组(低温循环阻断,n = 8)和N组(常温体外循环,n = 9)。H组院内死亡率为12.5%,N组为11.1%。两组手术时间相似,但N组体外循环时间显著短于H组(p < 0.05)。N组有1例患者发生术后截瘫。除1例术前透析患者外,H组无术后肾功能不全发生,而N组有6例患者发生。N组术后肌酐水平显著高于H组。H组有3例患者需要气管切开。我们应用低温体外循环和循环阻断治疗弥漫型胸腹主动脉瘤的经验证实了该技术的安全性和有效性。尽管呼吸并发症仍然是一个问题,但该技术被认为对肾脏有保护作用。