Yagmur C, Miman M C, Karatas E, Akarcay M, Erdem T, Ozturan O
Department of Nuclear Medicine, Inonu University School of Medicine, Malatya, Turkey.
J Laryngol Otol. 2004 Feb;118(2):102-5. doi: 10.1258/002221504772784531.
The aim of this study is to compare the scintigraphic results of a denervated submandibular gland with the contralateral normal side in patients with unilateral chorda tympani damage. Sixteen patients (11 women and five men with a mean age of 27) with unilateral proven chorda tympani damage during their previous ear surgery were included in the study. The perfusion ratio (PR), concentration ratio (CR) and stimulated excretion ratio (SER) were calculated scintigraphically and the results from the salivary glands on opposite sides were compared. For submandibular glands, the perfusion ratio (PR), concentration ratio (CR) and stimulated excretion ratio (SER) were found to be 0.65 +/- 0.21, 0.70 +/- 0.21, 0.79 +/- 0.37, respectively. All ratios resulted from statistically decreased radioactivity accumulation on the affected side (p<0.05). Chorda tympani damage negatively affects the function of the ipsilateral submandibular glands despite the absence of atrophy. Dynamic salivary gland scintigraphy is a practical and valuable method of disclosing the decreased capacity of perfusion, concentration and secretion function in unilateral neurological deprivation.
本研究旨在比较单侧鼓索神经损伤患者失神经支配的下颌下腺与对侧正常下颌下腺的闪烁扫描结果。16例患者（11名女性和5名男性，平均年龄27岁）纳入研究，这些患者在既往耳部手术中证实存在单侧鼓索神经损伤。通过闪烁扫描计算灌注率（PR）、浓度率（CR）和刺激排泄率（SER），并比较两侧唾液腺的结果。对于下颌下腺，灌注率（PR）、浓度率（CR）和刺激排泄率（SER）分别为0.65±0.21、0.70±0.21、0.79±0.37。所有比率均显示患侧放射性积聚在统计学上减少（p<0.05）。尽管没有萎缩，鼓索神经损伤仍会对同侧下颌下腺的功能产生负面影响。动态唾液腺闪烁扫描是一种实用且有价值的方法，可揭示单侧神经剥夺时灌注、浓缩和分泌功能的降低。
