一名8岁使用鞘内注射巴氯芬泵的患儿出现巴氯芬中毒。

Baclofen toxicity in an 8-year-old with an intrathecal baclofen pump.

作者信息

Yeh Ronald N, Nypaver Michele M, Deegan Thomas J, Ayyangar Rita

机构信息

Department of Emergency Medicine, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

J Emerg Med. 2004 Feb;26(2):163-7. doi: 10.1016/j.jemermed.2003.07.009.

DOI:10.1016/j.jemermed.2003.07.009

PMID:14980337

Abstract

Baclofen delivered by intrathecal pumps (ITB) is increasingly being utilized in the pediatric population, however, resources and education to support problems with these devices are limited. Typical management strategies for systemic baclofen overdose include removal of baclofen from the device reservoir or removal of cerebrospinal fluid from the adjacent device catheter. Appropriate care of these patients requires awareness of the clinical patterns of toxicity and mechanics of the ITB pump delivery system. This report describes the clinical presentation, unfamiliar dilemmas, and the management of a pediatric patient with intrathecal baclofen toxicity, noting problems that may arise in the care of these patients.

摘要

鞘内泵（ITB）输送的巴氯芬在儿科人群中的使用越来越多，然而，支持处理这些装置相关问题的资源和教育却很有限。全身性巴氯芬过量的典型管理策略包括从装置储液器中取出巴氯芬或从相邻的装置导管中抽出脑脊液。对这些患者进行恰当护理需要了解毒性的临床模式和ITB泵输送系统的机制。本报告描述了一名鞘内注射巴氯芬中毒的儿科患者的临床表现、罕见困境及处理情况，并指出了这些患者护理中可能出现的问题。