Jett G K, Miller A, Savino D, Gonwa T
Department of Cardiothoracic Surgery, Baylor University Medical Center, Dallas, Texas 75246.
J Heart Lung Transplant. 1992 Jul-Aug;11(4 Pt 1):733-8.
Reported is a case of acute fulminant lymphocytic myocarditis with profound circulatory compromise that was successfully reversed by treatment with OKT3 monoclonal antibody. The patient was supported with biventricular assist devices while being treated with the monoclonal antibody. The patient had remarkable recovery of ventricular function, which allowed for the removal of the device after 8 days of support. This case shows the success of combined technologies of monoclonal antibody and mechanical circulatory support to treat a potentially fatal disease process.
报告了一例急性暴发性淋巴细胞性心肌炎伴严重循环功能障碍的病例，该病例通过使用OKT3单克隆抗体治疗成功逆转。患者在接受单克隆抗体治疗期间接受了双心室辅助装置支持。患者心室功能显著恢复，在支持治疗8天后得以撤除该装置。本病例显示了单克隆抗体与机械循环支持联合技术治疗潜在致命疾病过程的成功。
