Sidel'nikov V O, Batkin A A, Paramonov B A, Matveenko A V, Klimov A G, Tarasenko M Iu, Kallistov D B, Zinov'ev E V, Admakin A L, Petrachkov S A
Voen Med Zh. 2003 Dec;324(12):34-9, 96.
The article is devoted to the review of main directions of anti-shock therapy improvement for patients with severe burns. It is shown that the treatment efficiency can be considerably increased both by optimization of infusion volume and by the use of modern infusion drugs with anti-hypoxic and anti-oxidant effects. The use of anti-hypoxic and anti-oxidant drugs permits to change the burn shock course and to decrease its duration. Decrease in severity of tissue hypoxia, prevention of cellular membrane injury interrupt one of the circuits of burn disease pathogenesis and create the favorable conditions for realization of acute adaptation mechanisms in terms of traumatic disease conception. The modern schemes of anti-shock therapy approved at the department of thermal injuries were used in the treatment of casualties with combined burns after the armed conflict in the territory of Chechnia (1999-2001).
本文致力于综述重度烧伤患者抗休克治疗的主要改进方向。结果表明，通过优化输液量以及使用具有抗缺氧和抗氧化作用的现代输液药物，可显著提高治疗效果。使用抗缺氧和抗氧化药物能够改变烧伤休克病程并缩短其持续时间。组织缺氧严重程度的降低以及细胞膜损伤的预防打断了烧伤疾病发病机制的其中一个环节，并根据创伤性疾病的概念为急性适应机制的实现创造了有利条件。在车臣境内武装冲突（1999 - 2001年）后，热损伤科批准的现代抗休克治疗方案被用于治疗合并烧伤的伤员。
