Benumof J L, Gaughan S D, Ozaki G
Department of Anesthesiology, University of California, San Diego.
J Cardiothorac Vasc Anesth. 1992 Aug;6(4):404-8. doi: 10.1016/1053-0770(92)90004-q.
The resting volume and diameter of the bronchial blocker cuff (defined as inflation of the cuff to just its natural shape) of the Univent (Fuji Systems Corp, Tokyo, Japan) tube are 2 mL and 5 mm. However, much larger inflation volumes may be required to seal an adult mainstem bronchus and the surface area of contact between the resultant spherical or ellipsoid-shaped cuff and the wall of the mainstem bronchus may be small and susceptible to leak with the application of high proximal airway pressures. This experiment determined the relationship among airway diameter, proximal airway pressure, inflation volume of the bronchial blocker cuff, and leakage of air around the bronchial blocker cuff in an in vitro model. The experimental model consisted of silicon tubing of 12.8-, 16.0-, and 19.2-mm ID as the mainstem bronchus. The main tracheal cuff sealed the Univent tube into the proximal end of the mainstem bronchus and the bronchial blocker cuff was inflated with various volumes near the distal end of the mainstem bronchus. The space between the tracheal cuff and the bronchial blocker cuff was then progressively pressurized in either a static or pulsed manner. The very distal end of the bronchus was functionally submerged under a beaker of water so that a bronchial blocker cuff leak would be indicated by bubbling. It was found that the Univent bronchial blocker cuff sealed the 12.8- and 16.0-mm ID mainstem bronchi against airway pressures as great as 100 cmH2O, with inflation volumes that were within the manufacturer's recommendation of 6 to 7 mL.(ABSTRACT TRUNCATED AT 250 WORDS)
Univent（日本东京富士系统公司）导管的支气管阻塞器套囊的静息容积和直径（定义为套囊充气至其自然形状）分别为2 mL和5 mm。然而，封堵成人主支气管可能需要大得多的充气量，并且由此形成的球形或椭圆形套囊与主支气管壁之间的接触表面积可能较小，在近端气道压力较高时容易漏气。本实验在体外模型中确定了气道直径、近端气道压力、支气管阻塞器套囊充气量以及支气管阻塞器套囊周围漏气之间的关系。实验模型由内径为12.8、16.0和19.2 mm的硅管作为主支气管组成。主气管套囊将Univent导管密封在主支气管的近端，支气管阻塞器套囊在主支气管远端附近用不同体积充气。然后以静态或脉冲方式对气管套囊和支气管阻塞器套囊之间的空间逐渐加压。支气管的最远端在功能上浸没在一杯水下，这样支气管阻塞器套囊漏气会通过冒泡显示出来。结果发现，Univent支气管阻塞器套囊在充气量在制造商推荐的6至7 mL范围内时，能够封堵内径为12.8和16.0 mm的主支气管，抵抗高达100 cmH2O的气道压力。（摘要截短于250字）
