在一名患有外阴癌且仅有一个阳性淋巴结的患者中，采用放射性示踪剂和蓝色染料联合技术检测前哨淋巴结失败。
Failure in the detection of the sentinel lymph node with a combined technique of radioactive tracer and blue dye in a patient with cancer of the vulva and a single positive lymph node.
作者信息
Fons G, ter Rahe B, Sloof G, de Hullu J, van der Velden J
机构信息
Department of Gynaecology and Obstetrics, Academic Medical Centre, Amsterdam, The Netherlands.
出版信息
Gynecol Oncol. 2004 Mar;92(3):981-4. doi: 10.1016/j.ygyno.2003.12.006.
BACKGROUND
In early stage vulvar cancer, the sentinel lymph node procedure with a radioactive tracer appears to be a promising new diagnostic tool to predict lymph node status. No detection failures have been published so far in vulvar cancer. We recently experienced failure in the detection of the sentinel lymph node in a patient with a positive lymph node.
CASE
A 75-year-old patient with a clinical T2N0M0 squamous cell carcinoma replacing the clitoris underwent a sentinel node procedure. A sentinel node was detected only at one groin. An exploration of the other groin showed a positive lymph node totally replaced by tumor.
CONCLUSION
In the case we present, stasis of the lymph flow might be the leading cause of the failure of the sentinel lymph node procedure.
背景
在早期外阴癌中，使用放射性示踪剂的前哨淋巴结手术似乎是一种有前景的预测淋巴结状态的新诊断工具。迄今为止，外阴癌尚无检测失败的报道。我们最近遇到一例淋巴结阳性患者前哨淋巴结检测失败的情况。
病例
一名75岁临床诊断为T2N0M0的鳞状细胞癌累及阴蒂的患者接受了前哨淋巴结手术。仅在一侧腹股沟检测到一个前哨淋巴结。对另一侧腹股沟进行探查发现一个被肿瘤完全取代的阳性淋巴结。
结论
在我们所呈现的病例中，淋巴流淤滞可能是前哨淋巴结手术失败的主要原因。
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