Gottrand F, Turck D, Mitchell V, Farriaux J P
Service de Pédiatrie, Gastroentérologie Pédiatrique et Génétique Médicale, Hôpital Claude Huriez, Lille, France.
Acta Paediatr. 1992 May;81(5):399-401. doi: 10.1111/j.1651-2227.1992.tb12257.x.
We analyzed the results of 607 small bowel biopsies performed over a seven-year period: 284 biopsies were obtained using a fiberendoscope and 323 biopsies using a Watson capsule. Three to six specimens were removed during endoscopy. The biopsy fragments obtained with the fiberendoscope were deeper than those obtained with the Watson capsule (p less than 0.0001) and were more often located in the duodenum (p less than 0.0001). The failure rate of the fiberendoscope biopsies (1%) was lower than for the Watson capsule biopsies (9%) (p less than 0.0001). Multiple biopsies increased the diagnostic value of fiberendoscopy which was 95% versus 85% for Watson capsule. The mean duration of the endoscopic procedure recorded in 30 children was 6.5 min for four to six samples, i.e. 1.5 min per biopsy specimen. Fiberendoscopy appears to be an efficient and safe method for performing small bowel biopsies in infants and children.
我们分析了在七年时间内进行的607例小肠活检的结果：其中284例活检是使用纤维内镜获取的，323例活检是使用沃森胶囊进行的。在内镜检查过程中取出了三到六个标本。通过纤维内镜获得的活检碎片比通过沃森胶囊获得的更深（p小于0.0001），并且更常位于十二指肠（p小于0.0001）。纤维内镜活检的失败率（1%）低于沃森胶囊活检（9%）（p小于0.0001）。多次活检提高了纤维内镜检查的诊断价值，纤维内镜检查的诊断价值为95%，而沃森胶囊为85%。记录的30名儿童内镜检查的平均持续时间为，取四到六个样本时为6.5分钟，即每个活检标本1.5分钟。纤维内镜检查似乎是在婴儿和儿童中进行小肠活检的一种有效且安全的方法。
