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[肝病血瘀证的临床病理特征及肝功能变化]

[Characteristics of clinical pathology and changes of liver function in blood stasis syndrome in liver diseases].

作者信息

Zhang C Z, Wu S S, Luo X L

机构信息

Institute of Viscera in TCM and Liver Diseases, Hubei College of TCM, Wuhan.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1992 Apr;12(4):210-2, 196.

PMID:1498540
Abstract

The experimental study on 30 patients of the Blood Stasis Syndrome of liver diseases was discussed in this paper. Two characteristics were found. One was the pathological feature which manifested as follows: (1) DIAGNOSIS: the Blood Stasis Syndrome of liver disease was mainly diagnosed in the chronic active hepatitis and the early stage of cirrhosis of liver, while that of non-Blood Stasis was mainly observed in the chronic persistent hepatitis (P less than 0.01); (2) Pathological change: The histological changes such as piecemeal necrosis, bridging necrosis, the destruction of limiting plate, eosinophilic change, etc. It was more obvious in the Blood Stasis group than that with non-Blood Stasis Syndrome (P less than 0.01), (3) The manifestation of Blood Stasis Syndrome was not in parallel with the severity of the liver disease. The another characteristic was the changes of liver function, which expressed more markedly in the Blood Stasis group with higher level of SGPT, lower ratio of A/G and increased globulin, they were more obvious than that in non-Blood Stasis group (P less than 0.01).

摘要

本文探讨了对30例肝病血瘀证患者的实验研究。发现了两个特点。一是病理特征,表现如下:(1)诊断:肝病血瘀证主要诊断于慢性活动性肝炎和早期肝硬化,而非血瘀证主要见于慢性持续性肝炎(P<0.01);(2)病理变化:如碎片状坏死、桥接坏死、界板破坏、嗜酸性变等组织学变化,血瘀组比非血瘀证组更明显(P<0.01);(3)血瘀证的表现与肝病严重程度不平行。另一个特点是肝功能变化,在血瘀组中表现更明显,谷丙转氨酶水平较高、白蛋白/球蛋白比值较低且球蛋白升高,比非血瘀组更明显(P<0.01)。

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