Miyake Fumiko Y, Yakushijin Kenichi, Horne David A
Department of Chemistry, Oregon State University, Corvallis, OR 97331, USA.
Org Lett. 2004 Mar 4;6(5):711-3. doi: 10.1021/ol030138x.
The preparation of 2-halotryptamines from tryptamine is described. New stereoselective intramolecular iminium ion spirocyclization methodology for the construction of spiro[pyrrolidine-3,3'-oxindoles] is outlined in synthetic studies of elacomine (1) and isoelacomine (2). [reaction: see text]
本文描述了从色胺制备2-卤代色胺的方法。在对伊拉可明(1)和异伊拉可明(2)的合成研究中,概述了构建螺[吡咯烷-3,3'-氧化吲哚]的新的立体选择性分子内亚胺离子螺环化方法。[反应:见正文]