使用参考源法测定核医学中重要放射性核素的半衰期。
Use of the reference source method to determine the half-lives of radionuclides of importance in nuclear medicine.
作者信息
da Silva Mônica A L, de Almeida Maria C M, da Silva Carlos J, Delgado José U
机构信息
Instituto Militar de Engenharia-IME, Pça Gal. Tibúrcio, s/n - Urca, Rio de Janeiro, Brazil.
出版信息
Appl Radiat Isot. 2004 Feb-Apr;60(2-4):301-5. doi: 10.1016/j.apradiso.2003.11.032.
The reference source method associated with HPGe gamma-ray spectrometric techniques has been applied to half-life determinations of radionuclides used in nuclear medicine. Simultaneous measurements were undertaken for radiopharmaceutical nuclides such as 67Ga, 99Tcm, 123I, 131I and another radionuclide as reference. Besides optimizing the analysis time, this procedure was shown to be independent of the instrumental technique, environmental and radiochemical impurity interferences for most radionuclides. However, some restrictions were observed in samples that contained impurities with the same emission energy or an energy that was very close to the energy of the radionuclide to be measured. The measurement conditions improved the quoted accuracy of the half-life by reducing the type B component uncertainty.
与高纯锗γ射线能谱技术相关的参考源法已应用于核医学中使用的放射性核素的半衰期测定。对放射性药物核素如67Ga、99Tcm、123I、131I以及另一种作为参考的放射性核素进行了同步测量。除了优化分析时间外，该程序还被证明对大多数放射性核素而言，不受仪器技术、环境和放射化学杂质干扰的影响。然而，在含有发射能量相同或与待测放射性核素能量非常接近的杂质的样品中观察到了一些限制。测量条件通过降低B类分量不确定度提高了所引用半衰期的准确性。
Zotero 插件