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[严重机械创伤患者脂质代谢指标变化的特征]

[The characteristics of changes in lipid metabolism indices of patients with severe mechanical trauma].

作者信息

Moroz V V, Bessekeev A A, Molchanova L V, Shcherbakova L N

出版信息

Anesteziol Reanimatol. 2003 Nov-Dec(6):4-7.

Abstract

The paper contains the study results of some lipid-metabolism indices in patients with severe mechanical injury. Changing concentrations of total cholesterol, triglycerides and of different lipoprotein fractions in blood plasma are demonstrated. It was established that the investigated lipid-metabolism indices reflect a degree of liver malfunction in severely impaired homeostasis. It can be stated on the basis of comparing the study results with the clinical outcome that the dynamic concentration of total cholesterol in blood plasma is an important prognostication factor. Changing ratios of high-density lipoproteins, low-density lipoproteins and extra-low-density lipoproteins were observed in survivors yet by day 15, which is indicative of a commencing dislipidemia.

摘要

本文包含了重度机械损伤患者某些脂质代谢指标的研究结果。展示了血浆中总胆固醇、甘油三酯及不同脂蛋白组分浓度的变化情况。已确定所研究的脂质代谢指标反映了严重内环境稳态受损时肝脏功能障碍的程度。根据研究结果与临床结局的比较可以得出,血浆中总胆固醇的动态浓度是一个重要的预后因素。在幸存者中,到第15天时观察到高密度脂蛋白、低密度脂蛋白和极低密度脂蛋白的比例发生了变化,这表明开始出现血脂异常。

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