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[体位改变后等比重0.5%布比卡因脊髓麻醉后的继发性颅内扩展]

[Secondary cranial extension after spinal anesthesia with isobaric 0.5% bupivacaine following postural change].

作者信息

Vicent O, Litz R J, Hübler M, Koch T

机构信息

Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Carl-Gustav-Carus, TU Dresden.

出版信息

Anaesthesist. 2003 Nov;52(11):1035-8. doi: 10.1007/s00101-003-0578-8.

DOI:10.1007/s00101-003-0578-8
PMID:14992091
Abstract

Inadvertent cranial extension of sympathetic and sensory block following posture change during spinal anaesthesia has been reported for isobaric as well as for hyperbaric local anaesthetics. We present the case of a patient who underwent surgical repair of a refracture of the tibia under spinal anaesthesia with 17.5 mg of isobaric 0.5% bupivacaine. The maximum level of sensory block (MLSB) reached T8 after 15 min. Following posture change into a 15 degrees anti-Trendelenburg position 35 min after lumbar puncture, the MLSB increased cranially for 10 segments and reached the C6 level after 10 min of anti-Trendelenburg position. The patient suffered from severe bradycardia and arterial hypotension which were treated with 6% hydroxyethyl starch, atropine and Akrinor. In addition, the patient developed respiratory insufficiency and was therefore intubated and the lungs were mechanically ventilated. The operation was performed uneventfully with the patient under general anaesthesia. At the end of surgery the trachea was extubated, and the patient was awake with stable hemodynamics, sufficient spontaneous ventilation and free of pain. MLSB reached the second lumbar dermatome. This case shows that after assumed fixation of the local anaesthetic an inadvertent extension of the MLSB following posture change is possible. Close surveillance is recommended for patients with central neuraxial blocks until the block is in complete remission. The mechanisms for inadvertent high extension of the MLSB following posture change are discussed.

摘要

在脊麻期间,无论是等比重还是重比重局部麻醉药,均有报道称体位改变后会出现交感神经和感觉阻滞意外向头端扩展的情况。我们报告一例患者,该患者在脊麻下使用17.5mg等比重0.5%布比卡因进行胫骨骨折修复手术。15分钟后感觉阻滞最高平面(MLSB)达T8。腰穿35分钟后,患者体位变为头高脚低15度位,之后MLSB向头端上升10个节段,在头高脚低位10分钟后达到C6平面。患者出现严重心动过缓和动脉低血压,给予6%羟乙基淀粉、阿托品和阿克立诺治疗。此外,患者出现呼吸功能不全,因此进行气管插管并机械通气。在全身麻醉下患者顺利完成手术。手术结束时气管拔管,患者清醒,血流动力学稳定,自主通气充分且无痛。MLSB降至第二腰椎皮节。该病例表明,在假定局部麻醉药已固定的情况下,体位改变后MLSB仍可能意外扩展。对于接受中枢神经轴阻滞的患者,建议密切监测直至阻滞完全消退。本文还讨论了体位改变后MLSB意外高度扩展的机制。

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本文引用的文献

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Cerebrospinal fluid density influences extent of plain bupivacaine spinal anesthesia.脑脊液密度影响布比卡因腰麻的范围。
Anesthesiology. 2002 Jun;96(6):1325-30. doi: 10.1097/00000542-200206000-00010.
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Ability of anaesthetists to identify a marked lumbar interspace.麻醉医生识别明显腰椎间隙的能力。
剖宫产术中体位对左旋布比卡因腰麻的影响
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Anaesthesist. 2004 Jul;53(7):656. doi: 10.1007/s00101-004-0677-1.
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Br J Anaesth. 2000 May;84(5):697-8.
5
Influence of sex on cerebrospinal fluid density in adults.性别对成人大脑脊髓液密度的影响。
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6
Cardiovascular effects of 6% hetastarch and lactated Ringer's solution during spinal anesthesia.脊髓麻醉期间6%羟乙基淀粉和乳酸林格氏液对心血管的影响。
Reg Anesth Pain Med. 1999 Sep-Oct;24(5):399-404. doi: 10.1016/s1098-7339(99)90004-4.
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Lumbosacral cerebrospinal fluid volume is the primary determinant of sensory block extent and duration during spinal anesthesia.腰骶部脑脊液容量是脊髓麻醉期间感觉阻滞范围和持续时间的主要决定因素。
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