Burcoş T, Popa E, Zodieru Ileana, Bordea A, Voiculescu S, Angelescu N
Clinica chirurgicală a Spitalului Clinic Colţea.
Chirurgia (Bucur). 2003 Mar-Apr;98(2):109-18.
For a long time, breast-conserving surgery has been a subject of great interest and debate. Many researchers have tried to find strict criteria in selecting the patients who can benefit from such a treatment but this remains a goal to achieve in the future. In our surgical department, from 1984 to 2000, 1152 patients were diagnosed with breast cancer. 741 patients (64.1%) had advanced breast cancer and 411 patients (35.6%) were diagnosed in I and II stages. From the patients with early breast cancer only 57 (14.1%) had benefited of conservative surgery combined with adjuvant radiotherapy and chemotherapy. All patients received hormonotherapy. The surgical treatment consisted in a broad sectorectomy and axillary lymphadenectomy in all cases. We present the criteria for selecting patients in our study. The patients were followed for 2-5 years, with a mean period of 48 months and there were no significant differences between the trial with mamectomy and that with conservative surgery. There is presented a brief review of the literature in this field. Our conclusion is that the conservative surgery for breast cancer is a good method, which can be applied for selected patients and with a good follow-up.
长期以来,保乳手术一直是备受关注和争议的话题。许多研究人员试图找到严格的标准来筛选能从这种治疗中获益的患者,但这仍是未来要实现的目标。在我们外科,1984年至2000年期间,有1152例患者被诊断为乳腺癌。741例患者(64.1%)患有晚期乳腺癌,411例患者(35.6%)被诊断为I期和II期。在早期乳腺癌患者中,只有57例(14.1%)接受了保乳手术联合辅助放疗和化疗。所有患者均接受了激素治疗。所有病例的手术治疗均包括广泛切除和腋窝淋巴结清扫。我们介绍了本研究中患者的选择标准。患者随访2至5年,平均随访时间为48个月,乳房切除术试验和保乳手术试验之间无显著差异。本文对该领域的文献进行了简要综述。我们的结论是,乳腺癌保乳手术是一种很好的方法,可应用于经过挑选的患者,并进行良好的随访。