Kuralay Erkan, Bolcal Cengiz, Cingoz Faruk, Günay Celalettin, Yildirim Vedat, Kilic Selim, Ozal Ertugrul, Demirkilic Ufuk, Arslan Mehmet, Tatar Harun
Department of Cardiovascular Surgery, Gülhane Military Medical Academy, Ankara, Turkey.
Ann Thorac Surg. 2004 Mar;77(3):977-81; discussion 982. doi: 10.1016/j.athoracsur.2003.09.064.
Division of the sternum is primarily a blind procedure in reoperation and carries an increased risk of injury for major cardiac structures in the presence of adhesions between the posterior table and the heart.
Two hundred patients were randomly divided into two groups. Cardiopulmonary bypass was established through the femoral artery and vein in group 1 (n = 100) patients before sternal reentry. Carpentier dual-stage femoral venous return cannula was used in all group 1 patients. Cardiopulmonary bypass was performed after sternal reentry in group 2 (n = 100) patients.
Six severe cardiac injuries developed in group 2. Cardiopulmonary bypass time was 93 +/- 9 minutes in group 1 and 71 +/- 11 minutes in group 2 (p = 0.011), and the operation time was 155 +/- 23 minutes in group 1 and 185 +/- 32 minutes in group 2 (p = 0.024). Inotropic therapy was required in 52 patients in group 1 and 76 patients in group 2 (p = 0.032). Average chest drainage was 450 +/- 135 mL in group 1 and 850 +/- 250 mL in group 2 (p < 0.001). Average fresh whole blood transfusion was 3.3 +/- 1.2 U in group 1 and 5.8 +/- 0.9 U in group 2 (p = 0.033). Average intensive care unit stay was 2.2 +/- 1.3 days in group 1 and 4.5 +/- 2.3 days in group 2 (p = 0.025). Average hospital stay was 7.3 +/- 2.4 days in group 1 and 9.1 +/- 3.1 days for group 2 (p = 0.011).
Cardiopulmonary bypass by bicaval Carpentier femoral venous cannula before resternotomy not only allows adequate cardiopulmonary bypass flow but also significantly reduces the risk of cardiac injury and catastrophic hemorrhage and allows safe reopening. Although this procedure increases cardiopulmonary bypass time, the operation time, bleeding, and blood transfusion requirement are significantly reduced.
在再次手术中,胸骨劈开主要是一种盲目操作,在胸骨后板与心脏之间存在粘连的情况下,对主要心脏结构造成损伤的风险增加。
200例患者随机分为两组。第1组(n = 100)患者在胸骨再次切开前经股动脉和股静脉建立体外循环。第1组所有患者均使用卡彭蒂埃双阶段股静脉回流插管。第2组(n = 100)患者在胸骨再次切开后进行体外循环。
第2组发生6例严重心脏损伤。第1组体外循环时间为93±9分钟,第2组为71±11分钟(p = 0.011),第1组手术时间为155±23分钟,第2组为185±32分钟(p = 0.024)。第1组52例患者和第2组76例患者需要进行强心治疗(p = 0.032)。第1组平均胸腔引流量为450±135 mL,第2组为850±250 mL(p < 0.001)。第1组平均新鲜全血输注量为3.3±1.2 U,第2组为5.8±0.9 U(p = 0.033)。第1组平均重症监护病房停留时间为2.2±1.3天,第2组为4.5±2.3天(p = 0.025)。第1组平均住院时间为7.3±2.4天,第2组为9.1±3.1天(p = 0.011)。
在再次胸骨切开术前通过双腔卡彭蒂埃股静脉插管进行体外循环,不仅能提供足够的体外循环流量,还能显著降低心脏损伤和灾难性出血的风险,并实现安全的再次切开。虽然该操作会增加体外循环时间,但手术时间、出血量和输血需求量均显著减少。