Department of Cardiothoracic Surgery, Golden Jubilee National Hospital, Glasgow, Scotland.
Scottish National Advanced Heart Failure Service, Golden Jubilee National Hospital, Glasgow, Scotland.
Heart Fail Rev. 2019 Sep;24(5):805-820. doi: 10.1007/s10741-019-09794-1.
Primary graft dysfunction (PGD) remains the leading cause of early mortality post-heart transplantation. Despite improvements in mechanical circulatory support and critical care measures, the rate of PGD remains significant. A recent consensus statement by the International Society of Heart and Lung Transplantation (ISHLT) has formulated a definition for PGD. Five years on, we look at current concepts and future directions of PGD in the current era of transplantation.
原发性移植物功能障碍(PGD)仍然是心脏移植术后早期死亡的主要原因。尽管机械循环支持和重症监护措施有所改善,但 PGD 的发生率仍然很高。国际心肺移植学会(ISHLT)最近发表了一份共识声明,为 PGD 制定了定义。五年过去了,我们在当前的移植时代探讨了 PGD 的现有概念和未来方向。