Weeber Edwin J, Levenson Jonathan M, Sweatt J David
Division of Neuroscience, Baylor College of Medicine 1 Baylor Plaza, Houston, TX 77030, USA.
Mol Interv. 2002 Oct;2(6):376-91, 339. doi: 10.1124/mi.2.6.376.
Our understanding of the molecular underpinnings of human cognition has been greatly aided by the convergent synergy of clinical, genetic, and signaling research. By identifying the mutated genes that give rise to syndromes of mental retardation or cognitive defects in patients, and by placing the associated gene products within signaling networks, researchers are piecing together how learning occurs and how memories are formed and sustained.
临床、遗传和信号研究的协同作用极大地促进了我们对人类认知分子基础的理解。通过识别导致患者智力迟钝或认知缺陷综合征的突变基因,并将相关基因产物置于信号网络中,研究人员正在拼凑学习是如何发生的,以及记忆是如何形成和维持的。