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超重、种族与学龄儿童高血压患病率

Overweight, ethnicity, and the prevalence of hypertension in school-aged children.

作者信息

Sorof Jonathan M, Lai Dejian, Turner Jennifer, Poffenbarger Tim, Portman Ronald J

机构信息

Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, University of Texas Health Science Center, Houston, Texas, USA.

出版信息

Pediatrics. 2004 Mar;113(3 Pt 1):475-82. doi: 10.1542/peds.113.3.475.

Abstract

OBJECTIVES

To describe the current prevalence of pediatric hypertension and the relationships between gender, ethnicity, overweight, and blood pressure.

METHODS

School-based screening was performed in 5102 children (13.5 +/- 1.7 years) from May through November 2002. Age, gender, ethnicity, weight, and height were ascertained, and body mass index (BMI) was calculated as weight (kg)/height (m2). Overweight was defined as BMI > or =95th percentile. Students with blood pressure >95th percentile on the first screening underwent a second screening 1 to 2 weeks later, and then a third screening if blood pressure was >95th percentile at the second screening.

RESULTS

Ethnicity distribution was 44% white, 25% Hispanic, 22% African American, and 7% Asian. Overall, overweight prevalence was 20%, which varied significantly by ethnicity (31% Hispanic, 20% African American, 15% white, and 11% Asian). The prevalence of elevated blood pressure after first, second, and third screenings was 19.4%, 9.5%, and 4.5%, respectively. Elevated blood pressure on first screening was highest among Hispanics (25%) and lowest among Asians (14%). Ethnic differences in the prevalence of hypertension (elevated blood pressure on 3 screenings) were not significant after controlling for overweight. The prevalence of hypertension increased progressively as the BMI percentile increased from < or =5th percentile (2%) to > or =95th percentile (11%). After adjustment for gender, ethnicity, overweight, and age, the relative risk of hypertension was significant for gender (relative risk: 1.50; confidence interval: 1.15, 1.95) and overweight (relative risk: 3.26; confidence interval: 2.50, 4.24).

CONCLUSIONS

These results confirm an evolving epidemic of cardiovascular risk in youth, as evidenced by an increase in the prevalence of overweight and hypertension, notably among ethnic minority children.

摘要

目的

描述儿童高血压的当前患病率以及性别、种族、超重与血压之间的关系。

方法

2002年5月至11月,对5102名儿童(13.5±1.7岁)进行了基于学校的筛查。确定年龄、性别、种族、体重和身高,并计算体重指数(BMI),即体重(千克)/身高(米²)。超重定义为BMI≥第95百分位数。首次筛查时血压>第95百分位数的学生在1至2周后进行第二次筛查,如果第二次筛查时血压>第95百分位数,则进行第三次筛查。

结果

种族分布为44%白人、25%西班牙裔、22%非裔美国人、7%亚裔。总体而言,超重患病率为20%,因种族而异(西班牙裔为31%,非裔美国人为20%,白人为15%,亚裔为11%)。第一次、第二次和第三次筛查后血压升高的患病率分别为19.4%、9.5%和4.5%。首次筛查时血压升高在西班牙裔中最高(25%),在亚裔中最低(14%)。在控制超重因素后,高血压患病率(三次筛查时血压升高)的种族差异不显著。随着BMI百分位数从≤第5百分位数(2%)增加到≥第95百分位数(11%),高血压患病率逐渐上升。在对性别、种族、超重和年龄进行调整后,高血压的相对风险在性别方面具有统计学意义(相对风险:1.50;置信区间:1.15,1.95),在超重方面也具有统计学意义(相对风险:3.26;置信区间:2.50,4.24)。

结论

这些结果证实了青少年心血管疾病风险呈不断发展的流行趋势,超重和高血压患病率的增加尤其在少数族裔儿童中表现明显,即为明证。

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