Sorof Jonathan M, Lai Dejian, Turner Jennifer, Poffenbarger Tim, Portman Ronald J
Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, University of Texas Health Science Center, Houston, Texas, USA.
Pediatrics. 2004 Mar;113(3 Pt 1):475-82. doi: 10.1542/peds.113.3.475.
To describe the current prevalence of pediatric hypertension and the relationships between gender, ethnicity, overweight, and blood pressure.
School-based screening was performed in 5102 children (13.5 +/- 1.7 years) from May through November 2002. Age, gender, ethnicity, weight, and height were ascertained, and body mass index (BMI) was calculated as weight (kg)/height (m2). Overweight was defined as BMI > or =95th percentile. Students with blood pressure >95th percentile on the first screening underwent a second screening 1 to 2 weeks later, and then a third screening if blood pressure was >95th percentile at the second screening.
Ethnicity distribution was 44% white, 25% Hispanic, 22% African American, and 7% Asian. Overall, overweight prevalence was 20%, which varied significantly by ethnicity (31% Hispanic, 20% African American, 15% white, and 11% Asian). The prevalence of elevated blood pressure after first, second, and third screenings was 19.4%, 9.5%, and 4.5%, respectively. Elevated blood pressure on first screening was highest among Hispanics (25%) and lowest among Asians (14%). Ethnic differences in the prevalence of hypertension (elevated blood pressure on 3 screenings) were not significant after controlling for overweight. The prevalence of hypertension increased progressively as the BMI percentile increased from < or =5th percentile (2%) to > or =95th percentile (11%). After adjustment for gender, ethnicity, overweight, and age, the relative risk of hypertension was significant for gender (relative risk: 1.50; confidence interval: 1.15, 1.95) and overweight (relative risk: 3.26; confidence interval: 2.50, 4.24).
These results confirm an evolving epidemic of cardiovascular risk in youth, as evidenced by an increase in the prevalence of overweight and hypertension, notably among ethnic minority children.
描述儿童高血压的当前患病率以及性别、种族、超重与血压之间的关系。
2002年5月至11月,对5102名儿童(13.5±1.7岁)进行了基于学校的筛查。确定年龄、性别、种族、体重和身高,并计算体重指数(BMI),即体重(千克)/身高(米²)。超重定义为BMI≥第95百分位数。首次筛查时血压>第95百分位数的学生在1至2周后进行第二次筛查,如果第二次筛查时血压>第95百分位数,则进行第三次筛查。
种族分布为44%白人、25%西班牙裔、22%非裔美国人、7%亚裔。总体而言,超重患病率为20%,因种族而异(西班牙裔为31%,非裔美国人为20%,白人为15%,亚裔为11%)。第一次、第二次和第三次筛查后血压升高的患病率分别为19.4%、9.5%和4.5%。首次筛查时血压升高在西班牙裔中最高(25%),在亚裔中最低(14%)。在控制超重因素后,高血压患病率(三次筛查时血压升高)的种族差异不显著。随着BMI百分位数从≤第5百分位数(2%)增加到≥第95百分位数(11%),高血压患病率逐渐上升。在对性别、种族、超重和年龄进行调整后,高血压的相对风险在性别方面具有统计学意义(相对风险:1.50;置信区间:1.15,1.95),在超重方面也具有统计学意义(相对风险:3.26;置信区间:2.50,4.24)。
这些结果证实了青少年心血管疾病风险呈不断发展的流行趋势,超重和高血压患病率的增加尤其在少数族裔儿童中表现明显,即为明证。