Oster L, Horowitz Y S, Biderman S, Haddad J
Physics Department, Negev Academic College of Engineering, Beer-Sheva, Israel.
Australas Phys Eng Sci Med. 2003 Dec;26(4):173-8. doi: 10.1007/BF03179178.
We demonstrate the viability of the concept of using existing molecular nanostructures in thermoluminescent solid-state materials as solid-state nanodosimeters. The concept is based on mimicking radiobiology (specifically the ionization density dependence of double strand breaks in DNA) by using the similar ionization density dependence of simultaneous electron-hole capture in spatially correlated trapping and luminescent centres pairs in the thermoluminescence of LiF:Mg,Ti. This simultaneous electron-hole capture has been shown to lead to ionization density dependence in the relative intensity of peak 5a to peak 5 similar to the ratio of double-strand breaks to single-strand breaks for low energy He ions.
我们证明了在热释光固态材料中使用现有的分子纳米结构作为固态纳米剂量计这一概念的可行性。该概念基于通过利用LiF:Mg,Ti热释光中空间相关的俘获和发光中心对中同时发生的电子-空穴俘获的类似电离密度依赖性,来模拟放射生物学(特别是DNA中双链断裂的电离密度依赖性)。这种同时发生的电子-空穴俘获已被证明会导致5a峰与5峰相对强度的电离密度依赖性,类似于低能氦离子的双链断裂与单链断裂的比率。