冠状动脉斑块内的C反应蛋白通过冠状动脉循环提高自身血浆水平的潜在作用。
Possible contribution of C-reactive protein within coronary plaque to increasing its own plasma levels across coronary circulation.
作者信息
Ishikawa Tetsunori, Imamura Takuroh, Hatakeyama Kinta, Date Haruhiko, Nagoshi Toshiro, Kawamoto Riichirou, Matsuyama Akihiko, Asada Yujiro, Eto Tanenao
机构信息
First Department of Internal Medicine, Miyazaki Medical College, Kiyotake, Miyazaki, Japan.
出版信息
Am J Cardiol. 2004 Mar 1;93(5):611-4. doi: 10.1016/j.amjcard.2003.11.030.
C-reactive protein (CRP) mRNA was detected in coronary plaque. Plasma CRP levels across the coronary circulation were increased much more in patients with unstable angina pectoris and somewhat more in those with stable angina pectoris compared with controls whose coronary arteries were angiographically normal. Thus, CRP within coronary plaque might contribute to increased plasma CRP levels across coronary circulation, particularly among patients with unstable angina pectoris.
在冠状动脉斑块中检测到C反应蛋白（CRP）信使核糖核酸。与冠状动脉造影正常的对照组相比，不稳定型心绞痛患者冠状动脉循环中的血浆CRP水平升高更为明显，稳定型心绞痛患者的升高幅度稍小。因此，冠状动脉斑块内的CRP可能导致冠状动脉循环中血浆CRP水平升高，尤其是在不稳定型心绞痛患者中。
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