采用直径2.25毫米的西罗莫司洗脱支架治疗极细血管（来自RESEARCH注册研究）。
Treatment of very small vessels with 2.25-mm diameter sirolimus-eluting stents (from the RESEARCH registry).
作者信息
Lemos Pedro A, Arampatzis Chourmouzios A, Saia Francesco, Hoye Angela, Degertekin Muzaffer, Tanabe Kengo, Lee Chi-Hang, Cummins Paul, Smits Pieter C, McFadden Eugène, Sianos Georgios, de Feyter Pim, van der Giessen Willem J, van Domburg Ron T, Serruys Patrick W
机构信息
Department of Cardiology, Thoraxcenter, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.
出版信息
Am J Cardiol. 2004 Mar 1;93(5):633-6. doi: 10.1016/j.amjcard.2003.11.037.
A total of 91 patients with 112 lesions received 2.25-mm sirolimus-eluting stents (SESs), and these lesions were compared with those treated with SESs of > or =2.5-mm diameter in the same procedure (n = 109). The reference diameters were 1.88 +/- 0.34 and 2.52 +/- 0.57 mm, respectively (p <0.01). At follow-up, the late lumen loss was 0.07 +/- 0.48 mm for the 2.25-mm SES versus 0.03 +/- 0.38 mm for the larger SES (p = 0.5), and the binary restenosis rate was 10.7% versus 3.9%, respectively (p = 0.1). The 12-month target lesion revascularization rate was 5.5%. In conclusion, 2.25-mm SESs were associated with low rates of clinical and angiographic late complications.
共有91例患者的112处病变接受了2.25毫米西罗莫司洗脱支架（SES）治疗，这些病变与在同一手术中接受直径大于或等于2.5毫米SES治疗的病变（n = 109）进行比较。参考直径分别为1.88±0.34毫米和2.52±0.57毫米（p<0.01）。随访时，2.25毫米SES的晚期管腔丢失为0.07±0.48毫米，而较大尺寸SES为0.03±0.38毫米（p = 0.5），二元再狭窄率分别为10.7%和3.9%（p = 0.1）。12个月时的靶病变血管重建率为5.5%。总之，2.25毫米SES与临床和血管造影晚期并发症的低发生率相关。
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