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[不同程度冠状动脉灌注下冠状动脉血管的功能和形态学特征]

[Functional and morphological characteristics of coronary vessels in varying degree of coronary perfusion].

作者信息

Orlova N M, Havrysh O S

出版信息

Fiziol Zh (1978). 1992 May-Jun;38(3):26-32.

PMID:1499757
Abstract

Limitation of coronary perfusion of different degree induces inhomogeneous changes in resistance of vessels in the hypoperfusing zone: an adequate dilatory regulatory reaction may be followed by an increase in resistance of the coronary vessels. An active component of diastolic coronary resistance used to analyze vascular reactions, rate and character of changes in resistance under conditions of coronary perfusion as well as histological and electron-microscopic estimation of the vascular wall state testify to reversibility and active character of the observed changes in coronary resistance including its increase. This increase is pathogenetically significant as it may induce further development of the coronary perfusion disorder.

摘要

不同程度的冠状动脉灌注受限会在灌注不足区域引起血管阻力的不均匀变化

在充分的扩张调节反应之后,冠状动脉阻力可能会增加。用于分析血管反应的舒张期冠状动脉阻力的活性成分、冠状动脉灌注条件下阻力变化的速率和特征,以及血管壁状态的组织学和电子显微镜评估,都证明了观察到的冠状动脉阻力变化(包括其增加)的可逆性和活性特征。这种增加在发病机制上具有重要意义,因为它可能会导致冠状动脉灌注障碍的进一步发展。

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