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[奥斯勒遗传性血管性水肿作为假性外科急腹症的罕见但可能病因]

[Osler's hereditary angioneurotic edema as rare but possible cause of false surgical acute abdomen].

作者信息

Gugilă I, Ruxanda Anca, Vasile L, Iordache Violeta

机构信息

Clinica III Chirurgie, Spitalul Clinic de Urgenţă Craiova, Bd. Mareşal Ion Antonescu, nr. 60, 1100, Craiova.

出版信息

Chirurgia (Bucur). 2003 Sep-Oct;98(5):437-41.

Abstract

The authors are presenting one case of Osler's hereditary angioneurotic oedema, rare genetic disease with dominant autosomal transmission linked to the 11-th chromosome, with clinical aspects resembling to those of surgical acute abdomen, with difficult diagnostic problems. The treatment consist in: fresh plasma administration, antihistaminic drugs and anabolic steroids. The simple laparotomy under general anaesthesia by orotraheal intubation being very dangerous. The patients with Osler's hereditary angioneurotic oedema must be followed-up by the allergology services and educated regarding the disease and it's risks to avoid diagnostic errors with following negative consequences.

摘要

作者报告了一例奥斯勒遗传性血管神经性水肿病例,这是一种罕见的常染色体显性遗传病,与第11号染色体相关,其临床症状与外科急腹症相似,诊断存在困难。治疗方法包括:输注新鲜血浆、使用抗组胺药物和合成代谢类固醇。在全身麻醉下行经口气管插管的单纯剖腹手术非常危险。患有奥斯勒遗传性血管神经性水肿的患者必须由过敏科进行随访,并接受有关该疾病及其风险的教育,以避免出现诊断错误及随之而来的不良后果。

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