[Gastric stromal tumors--Clinical and histopathological analysis of four cases].

Neagu S, Zărnescu N O, Costea R, Stamatoiu A, Badea V, Dumitrescu C, Grădinaru S, Sajin M, Ardeleanu C, Pelmuş M

Secţia Clinică Chirurgie II, Spitalul Universitar de Urgenţă Bucureşti Splaiul Independenţei, nr. 169, sector 5, Bucureşti.

Chirurgia (Bucur). 2003 Sep-Oct;98(5):443-51.

BACKGROUND

The aim of this study is to present our experience concerning a rare form of gastric tumor--gastrointestinal stromal tumor (GIST).

METHODOLOGY

We reviewed data of four patients with gastric stromal tumors, which have been admitted in our department from 1998-2002.

RESULTS

There were two females and two males with age of 75, 70, 65 and 63 years old. The average duration of symptoms until hospital admission was 7 days. During surgery we discovered proximal gastric tumors with 4, 5, 10 and 20 cm in largest diameter. We performed excision of the whole tumor with a security limit of 2 cm or gastric resection (one case), without limphadenectomy. One patient developed an anastomotic fistula with a good evolution under conservative treatment. All patients left the hospital in a good condition. Histopathological and immunohistochemical study diagnosed gastric stromal tumors by identifying the CD 117 maker. Postoperatively neither one of our patients received chemotherapy or radiotherapy. One female and one male patient died of peritoneal metastasis at nine months and respectively two years after operation. The other two patients are in a good condition up to date, without metastasis, one and respectively three years after surgical treatment. CONCLUSIOUS: Correct diagnosis, complete tumor resection and surveillance are essential steps in management of gastric stromal tumors.