Pion P D, Kittleson M D, Thomas W P, Skiles M L, Rogers Q R
Department of Medicine, School of Veterinary Medicine, University of California, Davis 95616.
J Am Vet Med Assoc. 1992 Jul 15;201(2):267-74.
Between October 1986 and September 1988, 37 cats with moderate to severe idiopathic myocardial failure (dilated cardiomyopathy) were evaluated prospectively. Low plasma taurine concentration and diet history including foods that can cause taurine deficiency were documented in most of the cats. Comparison with a retrospectively studied population of 33 cats with dilated cardiomyopathy diagnosed between 1980 and 1986 demonstrated that the clinical and historical findings in the 33 retrospectively studied cats were similar to those in the 37 cats studied prospectively. Clinical findings in the 2 groups were also similar to findings previously reported in the literature. Because clinical findings and diet history were similar in the prospective and retrospective groups, we believe that many cats in the latter group had diet-induced taurine deficiency. These findings support the conclusion that most cases of dilated cardiomyopathy in cats have a common etiopathogenesis related to diet and as such are preventable.
在1986年10月至1988年9月期间,对37只患有中度至重度特发性心肌衰竭(扩张型心肌病)的猫进行了前瞻性评估。大多数猫都记录了低血浆牛磺酸浓度以及饮食史,包括可能导致牛磺酸缺乏的食物。与1980年至1986年间回顾性研究的33只诊断为扩张型心肌病的猫的群体进行比较,结果表明,回顾性研究的33只猫的临床和病史与前瞻性研究的37只猫相似。两组的临床发现也与先前文献报道的结果相似。由于前瞻性和回顾性研究组的临床发现和饮食史相似,我们认为后一组中的许多猫患有饮食诱导的牛磺酸缺乏症。这些发现支持了这样的结论,即猫扩张型心肌病的大多数病例具有与饮食相关的共同发病机制,因此是可以预防的。