Bowden R G, Kingery P M, Rust D M
Baylor University, PO Box 97313, Waco, TX 76798, USA.
Public Health. 2004 Apr;118(3):225-9. doi: 10.1016/j.puhe.2003.07.001.
The purpose of this study was to compare total capillary, total venous, risk ratio, high-density lipoprotein and low-density lipoprotein measures of cholesterol to determine whether total capillary cholesterol is a valid measure to use in cholesterol screening. An announcement and a registration form were distributed with employee paychecks announcing a cholesterol-screening programme. Capillary and venous samples were collected from screening participants (n=285). Results indicated false negatives in total capillary cholesterol in 17.21-34.4% of cases compared with other methods of cholesterol measurement. Due to the high number of misclassifications, health educators should not use total capillary cholesterol as a predictor of risk for heart disease, nor as a measure for referral during cholesterol screenings.
本研究的目的是比较总毛细血管胆固醇、总静脉胆固醇、风险比、高密度脂蛋白和低密度脂蛋白胆固醇指标，以确定总毛细血管胆固醇是否是用于胆固醇筛查的有效指标。一份公告和一份登记表随员工工资单一起发放，宣布了一项胆固醇筛查计划。从筛查参与者（n = 285）中采集了毛细血管和静脉样本。结果表明，与其他胆固醇测量方法相比，总毛细血管胆固醇检测出现假阴性的情况占17.21%至34.4%。由于错误分类的数量较多，健康教育工作者不应将总毛细血管胆固醇用作心脏病风险的预测指标，也不应将其作为胆固醇筛查期间转诊的衡量标准。
