Lynch John E, Heyman Joseph S, Hargens Alan R
Luna Innovations, Inc., 130 Research Drive, Hampton, VA 23666, USA.
Physiol Meas. 2004 Feb;25(1):N1-9. doi: 10.1088/0967-3334/25/1/n01.
An ultrasonic device for the diagnosis of acute compartment syndrome is described and results on six human cadaveric legs are presented. The ultrasonic device uses a pulsed phase locked loop (PPLL) to measure sub-micrometer displacements of the fascia wall. These displacements occur as a result of volume expansion of the muscle compartment of the lower leg and are related to changes in intramuscular pressure (IMP). In the cadaveric tests, the PPLL detected changes in compartment diameter resulting from IMP changes of 1 mmHg and from infusions of 0.25 ml saline increments. Based on these results, the ultrasonic PPLL appears to have the potential to become a low-cost, portable and noninvasive alternative to current methods for diagnosing acute compartment syndrome.
本文描述了一种用于诊断急性骨筋膜室综合征的超声设备,并展示了对六条人类尸体下肢的检测结果。该超声设备使用脉冲锁相环(PPLL)来测量筋膜壁的亚微米级位移。这些位移是由于小腿肌肉室的容积扩张而产生的,并且与肌内压(IMP)的变化有关。在尸体试验中,PPLL检测到因IMP变化1 mmHg以及每次注入0.25 ml生理盐水增量而导致的骨筋膜室直径变化。基于这些结果,超声PPLL似乎有潜力成为一种低成本、便携式且无创的替代当前诊断急性骨筋膜室综合征方法的手段。