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从日抛型软性隐形眼镜成功转换为高透氧性硅水凝胶镜片连续佩戴的6个月随访。

A 6-month follow-up of successful refits from daily disposable soft contact lenses to continuous wear of high-Dk silicone-hydrogel lenses.

作者信息

Aakre Bente Monica, Ystenaes Ann E, Doughty Michael J, Austrheim Øyvind, Westerfjell Björn, Lie Monica T

机构信息

Department of Optometry and Visual Science, Buskerud University College, Frogsvei 41, PO Box 251, 3603 Kongsberg, Norway.

出版信息

Ophthalmic Physiol Opt. 2004 Mar;24(2):130-41. doi: 10.1111/j.1475-1313.2004.00185.x.

Abstract

PURPOSE

To compare, in routine optometric practice, the outcome of keeping successful soft contact lens (SCL) wearers in their lenses to re-fitting them with continuous wear of silicone hydrogel (SiH) lenses.

METHODS

Forty-nine successful daily disposable lens wearers were recruited; 19 continued to wear daily SCLs and 30 were refitted with high-Dk SiH lenses on a 30-day/night schedule. Patients were assessed at baseline, 3 and 6 months by slit lamp examination along with the Efron grading scales, and central corneal thickness (CCT) and the corneal endothelium were assessed by non-contact specular microscopy.

RESULTS

No substantial changes in subjective vision, refraction, visual acuity or overall lens comfort occurred for those completing the study, although five SiH lens wearers did discontinue due to reduced comfort, eyelid problems or seasonal allergy. Contact lens induced peripheral ulcers (CLPU) were observed in three patients in the first 3 months in the SiH lens group and these were also discontinued. Over the 6 month period, a complete set of records was obtained for 16 in each group. For those completing the study, lens dryness scores were variable, but there was a slight improvement in favour of SiH lenses. Small, but statistically significant, reductions in corneal staining, bulbar hyperaemia, and limbal neovascularisation in favour of the SiH lenses were also evident but mainly because of further increases in the daily lens wearers. Contact lens induced papillary conjunctivitis (CLPC) and corneal endothelial polymegethism were mild to moderate and showed slight increases in the daily lens wearers at 6 months.

CONCLUSIONS

The present studies confirm that the continuous wear of SiH lenses for up to 30 days can be considered as an alternative to daily disposable soft lens wear, but is not suitable for everyone.

摘要

目的

在常规验光实践中,比较让成功佩戴软性接触镜(SCL)的使用者继续佩戴现有镜片与为他们重新配镜以连续佩戴硅水凝胶(SiH)镜片的效果。

方法

招募了49名成功佩戴日抛型镜片的使用者;19人继续佩戴日抛型SCL,30人重新配镜并按照30天/夜的时间表佩戴高透氧性的SiH镜片。在基线、3个月和6个月时,通过裂隙灯检查及埃弗龙分级量表对患者进行评估,并用非接触式角膜内皮显微镜评估中央角膜厚度(CCT)和角膜内皮情况。

结果

完成研究的患者在主观视力、验光、视力或整体镜片舒适度方面没有实质性变化,不过有5名佩戴SiH镜片的使用者因舒适度下降、眼睑问题或季节性过敏而停止佩戴。在SiH镜片组中,有3名患者在最初3个月内出现了接触镜诱发的周边溃疡(CLPU),这些患者也停止了佩戴。在6个月期间,每组均有16人获得了完整的记录。对于完成研究的患者,镜片干燥评分各不相同,但SiH镜片组有轻微改善。SiH镜片组在角膜染色、球结膜充血和角膜缘新生血管方面有虽小但具有统计学意义的降低,这主要是因为日抛型镜片使用者的这些指标进一步升高。接触镜诱发的乳头性结膜炎(CLPC)和角膜内皮大小不均在6个月时为轻度至中度,且日抛型镜片使用者有轻微增加。

结论

本研究证实,连续佩戴SiH镜片长达30天可被视为日抛型软性接触镜佩戴的一种替代方式,但并非适用于所有人。

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