Minor Michael E, Ellozy Sharif, Carroccio Alfio, Oak Juliana, Chae Kristina, Agarwal Gautam, Surmay Ryan, Teodorescu Victoria, Morrissey Nicholas J, Jacobs Tikva, Lookstein Robert, Hollier Larry H, Marin Michael L
Department of Surgery, Division of Vascular Surgery, The Mount Sinai School of Medicine, New York, NY 10029, USA.
Arch Surg. 2004 Mar;139(3):308-14. doi: 10.1001/archsurg.139.3.308.
During the past decade, endovascular stent graft repair (EVSG) of abdominal aortic aneurysms has emerged as a less invasive and less morbid alternative to open surgical repair. We hypothesize that EVSG may become the treatment method of choice among patients older than 80 years.
Retrospective case series.
Major academic medical center with extensive experience in endovascular and open aortic aneurysm surgery.
During a 5-year period, EVSG was performed in 595 patients at our institution. One hundred fifty (25.2%) of these patients were older than 80 years. Our prospectively acquired database was reviewed with respect to the demographic, intraoperative, and outcome data of this elderly population.
Technical and clinical success, aneurysm-related events (aneurysm-related death, type I or type III endoleaks, aneurysm expansion, or aneurysm rupture), and secondary interventions.
There were 119 men (79.3%) and 31 women (20.7%) (mean age, 84.6 years). Mean aneurysm diameter was 6.7 cm. Comorbidities including chronic obstructive pulmonary disease, coronary artery disease, chronic renal insufficiency, peripheral vascular disease, hypertension, and hypercholesterolemia were common in these patients, with an average of 2.9 comorbid conditions per patient. Mean follow-up was 16.9 months (range, 1.0-61.4 months). One hundred forty-six patients (97.3%) received only regional anesthesia, and the average intraoperative blood loss was 369 mL. Average hospital and intensive care unit stays were 2.5 days and 0.1 day, respectively. The procedure was performed emergently in 3 patients, and each recovered uneventfully. There were 5 aborted procedures (3.3%) for technical reasons and 4 conversions to open aortic repair (2.6%). In addition to these aborted procedures, there were 2 additional technical failures resulting in a technical success rate of 95.3%. Endoleaks were common and included 9 type I (6.90%), 35 type II (24.10%), and 1 type III (0.69%). The majority either resolved spontaneously (type IIs) or with minimally invasive secondary intervention, which was performed in 13 patients. Perioperative local/vascular and systemic complications occurred in 16 (10.7%) and 8 (5.3%) patients, respectively. There were 5 perioperative deaths (3.3%)(<30 days postoperatively). Forty late deaths (26.7%)(>30 days postoperatively) occurred, which were unrelated to the EVSG procedure.
Endovascular repair of abdominal aortic aneurysms can be performed safely and successfully in the majority of octogenarians with relatively low complication rates. Improved EVSG devices and operator experience may make this procedure the treatment method of choice for patients in this age group who meet specific anatomical criteria.
在过去十年中,腹主动脉瘤的血管内支架移植物修复术(EVSG)已成为开放性手术修复的一种侵入性较小且病态较轻的替代方法。我们假设EVSG可能会成为80岁以上患者的首选治疗方法。
回顾性病例系列。
在血管内和开放性主动脉瘤手术方面有丰富经验的大型学术医疗中心。
在5年期间,我们机构对595例患者进行了EVSG。其中150例(25.2%)患者年龄超过80岁。我们对前瞻性收集的数据库进行了回顾,以获取该老年人群的人口统计学、术中及结果数据。
技术和临床成功率、动脉瘤相关事件(动脉瘤相关死亡、I型或III型内漏、动脉瘤扩张或动脉瘤破裂)以及二次干预。
有119名男性(79.3%)和31名女性(20.7%)(平均年龄84.6岁)。平均动脉瘤直径为6.7厘米。这些患者中常见的合并症包括慢性阻塞性肺疾病、冠状动脉疾病、慢性肾功能不全、外周血管疾病、高血压和高胆固醇血症,平均每位患者有2.9种合并症。平均随访时间为16.9个月(范围1.0 - 61.4个月)。146例患者(97.3%)仅接受了区域麻醉,平均术中失血量为369毫升。平均住院时间和重症监护病房停留时间分别为2.5天和0.1天。3例患者为急诊手术,均顺利康复。因技术原因有5例手术中止(3.3%),4例转为开放性主动脉修复(2.6%)。除了这些中止的手术外,还有2例额外的技术失败,导致技术成功率为95.3%。内漏很常见,并包括9例I型(6.90%)、35例II型(24.10%)和1例III型(0.69%)。大多数内漏(II型)要么自行消失,要么通过微创二次干预解决,13例患者接受了二次干预。围手术期局部/血管和全身并发症分别发生在16例(10.7%)和8例(5.3%)患者中。围手术期有5例死亡(3.3%)(术后<30天)。发生了40例晚期死亡(26.7%)(术后>30天),这些与EVSG手术无关。
腹主动脉瘤的血管内修复术可以在大多数八旬老人中安全、成功地进行,并发症发生率相对较低。改进的EVSG设备和术者经验可能使该手术成为符合特定解剖学标准的该年龄组患者的首选治疗方法。