Tiefenbacher Christiane P
Department of Cardiology, Ruprecht-Karls University Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.
Clin Res Cardiol. 2008 Apr;97(4):215-21. doi: 10.1007/s00392-007-0634-5. Epub 2008 Jan 14.
With increasing age of the general population, a higher awareness of the disease, better screening methods and the option of less invasive therapeutical strategies, the incidence of abdominal aortic aneurysms (AAA) is rising steadily. Since AAA is a disease of the elderly patient with generalized atherosclerosis, there is a high coincidence with other vascular morbidities. Especially the presence of coronary artery disease and concomitant left ventricular dysfunction proves many of those patients to be cardiac high risk patients with respect to an operative approach. On the other hand, a high coincidence of severe peripheral arterial occlusive disease might hamper the endovascular approach and endovascular therapy might carry a high risk for these patients as well. Therefore, it is of utmost importance to consider how and when cardiac high risk patients with AAA should be treated. In this review therefore special aspects such as the choice of medical treatment, the need of preoperative coronary revascularization and the situation in old patients are discussed in detail.
随着普通人群年龄的增长、对该疾病认识的提高、筛查方法的改进以及侵入性较小的治疗策略的出现,腹主动脉瘤(AAA)的发病率正在稳步上升。由于AAA是一种发生于患有全身性动脉粥样硬化的老年患者的疾病,它与其他血管疾病高度并发。特别是冠状动脉疾病的存在以及伴随的左心室功能障碍,证明许多此类患者在手术治疗方面属于心脏高风险患者。另一方面,严重外周动脉闭塞性疾病的高度并发可能会妨碍血管内治疗方法的实施,并且血管内治疗对这些患者也可能具有高风险。因此,考虑如何以及何时治疗患有AAA的心脏高风险患者至关重要。因此,在本综述中,将详细讨论诸如药物治疗的选择、术前冠状动脉血运重建的必要性以及老年患者的情况等特殊方面。