丁型肝炎病毒重叠感染在香港非药物滥用者中仍然很少见。

Hepatitis D virus superinfection remains a rare occurrence in non-drug abusers in Hong Kong.

作者信息

Lok A S, Wong A, Sporton S, Lai C L, Liu V, Chung H T

机构信息

Department of Medicine, University of Hong Kong, Queen Mary Hospital.

出版信息

J Hepatol. 1992 Mar;14(2-3):332-4. doi: 10.1016/0168-8278(92)90179-s.

DOI:10.1016/0168-8278(92)90179-s

PMID:1500697

Abstract

Recent studies from Taiwan reported an increased prevalence of hepatitis D virus (HDV) superinfection as well as a spread of HDV infection to non-drug abusers. We examined the current prevalence of HDV superinfection in Hong Kong by testing sera from a large cohort of patients with acute and chronic hepatitis B virus (HBV) infection, collected between January 1988 and December 1990, for IgG antibody to HDV (anti-HDV). Anti-HDV was detected in 13 (93%) of 14 parenteral drug abusers who had HBV-related chronic liver disease. However, anti-HDV was detected in only one (0.15%) of 664 non-drug abusers who had chronic HBV infection and none of 31% patients with acute hepatitis B. We concluded that HDV superinfection remains a rare occurrence in non-drug abusers in Hong Kong.

摘要

台湾近期的研究报告称，丁型肝炎病毒（HDV）重叠感染的患病率有所上升，且HDV感染已传播至非药物滥用者。我们通过检测1988年1月至1990年12月期间收集的一大群急慢性乙型肝炎病毒（HBV）感染患者的血清中抗HDV IgG抗体，来研究香港目前HDV重叠感染的患病率。在14例患有HBV相关慢性肝病的静脉注射药物滥用者中，有13例（93%）检测到抗HDV。然而，在664例患有慢性HBV感染的非药物滥用者中，仅1例（0.15%）检测到抗HDV，而在31%的急性乙型肝炎患者中均未检测到。我们得出结论，在香港，HDV重叠感染在非药物滥用者中仍然很少见。