Woodford E M, Wilson K A, Marriott J F
The Pharmacy Practice Research Group, The School of Pharmacy, Aston University, Birmingham B4 7ET, UK.
J Antimicrob Chemother. 2004 Apr;53(4):650-2. doi: 10.1093/jac/dkh152. Epub 2004 Mar 10.
To identify the types, prevalence and nature of antibiotic prescribing control documents within NHS hospitals in the UK.
A self-completion postal questionnaire was sent to each Chief Pharmacist at 465 NHS hospitals in 2001/2002. This contained questions covering hospital demographics, and hospital antibiotic prescribing control documentation, including format, dissemination, approval and review processes.
In total, 253 (54%) completed questionnaires were returned. Of these, 168 respondents' hospitals had an antibiotic formulary, 107 had a policy for antibiotic prescribing and 216 had guidelines on antibiotic use. All three types of antibiotic prescribing documents were used by 82 hospitals but 18 did not have any documents; 44% of formularies, 45% of policies and 35% of guidelines were available electronically. The Drug and Therapeutics Committee was the most frequently cited body for document approval and approximately one-third of documents had been approved during the current year of the questionnaire. Only about one-half of responding hospitals had an annual review of documents.
Despite publication of high-profile national guidance in response to growing concerns regarding antimicrobial resistance, there has been little increase in the use of antibiotic prescribing control documents in NHS hospitals over the past decade. It is clear that appropriate controls for antibiotic prescribing are not yet universally applied in the UK and recommendations for action have been proposed.
确定英国国民健康服务体系(NHS)医院内抗生素处方控制文件的类型、普及率和性质。
2001/2002年,向465家NHS医院的每位首席药剂师发送了一份自填式邮政问卷。问卷包含有关医院人口统计学以及医院抗生素处方控制文件的问题,包括格式、传播、批准和审查流程。
共收回253份(54%)完整问卷。其中,168位受访者所在医院有抗生素处方集,107家有抗生素处方政策,216家有抗生素使用指南。82家医院使用了所有三种类型的抗生素处方文件,但有18家没有任何文件;44%的处方集、45%的政策和35%的指南可通过电子方式获取。药物与治疗委员会是文件批准最常被提及的机构,约三分之一的文件在问卷当年获得批准。只有约一半的回复医院对文件进行年度审查。
尽管针对对抗菌素耐药性日益增长的担忧发布了备受瞩目的国家指南,但在过去十年中,NHS医院抗生素处方控制文件的使用几乎没有增加。显然,抗生素处方的适当控制在英国尚未普遍应用,已提出了行动建议。