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Drug discovery in reverse.

作者信息

Smith Caitlin

出版信息

Nature. 2004 Mar 11;428(6979):227. doi: 10.1038/428227a.

DOI:10.1038/428227a

PMID:15014516

Abstract

摘要

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相似文献

Drug discovery in reverse.

Nature. 2004 Mar 11;428(6979):227. doi: 10.1038/428227a.

Gene array screening for identification of drugs with low levels of adverse side effects.

Arch Toxicol. 2010 Apr;84(4):253-4. doi: 10.1007/s00204-010-0534-8.

[DNA microarrays--perspective of application for drug effectivity and safety evaluation].

Postepy Biochem. 2008;54(1):107-15.

Connecting the dots using gene-expression profiles.

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Nat Genet. 1999 Jan;21(1 Suppl):48-50. doi: 10.1038/4475.

Drug target identification: a question of biology.

Nature. 2004 Mar 11;428(6979):225-31. doi: 10.1038/428225a.

Novel genomic methods for drug discovery and mechanism-based toxicological assessment.

Curr Opin Drug Discov Devel. 2009 Jan;12(1):72-80.

Connecting genes, drugs and diseases.

Nat Biotechnol. 2006 Nov;24(11):1365-6. doi: 10.1038/nbt1106-1365.

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.

Science. 2006 Sep 29;313(5795):1929-35. doi: 10.1126/science.1132939.

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Nature. 2005 Sep 22;437(7058):491-3. doi: 10.1038/437491a.