Whelton Helen P, Ketley Clare E, McSweeney Fiona, O'Mullane Denis M
Oral Health Services Research Centre, University College Cork, Ireland.
Community Dent Oral Epidemiol. 2004 Apr;32 Suppl 1:9-18. doi: 10.1111/j.1600-0528.2004.00134.x.
Fluoride has played a key role in caries prevention for the past 50 years but excessive ingestion of fluoride during tooth development may lead to dental fluorosis. Throughout Europe many vehicles have been, and are currently, employed for optimal fluoride delivery including drinking water, toothpaste, fluoride supplements, salt and milk. Several indices, both descriptive and aetiological, have been developed and used for measuring fluorosis. This factor, combined with the lack of use of a standardized method for measurement of fluorosis, has made comparison between studies difficult and assessment of trends in fluorosis prevalence unreliable. Overall the evidence would appear to indicate, however, that diffuse enamel opacities are more prevalent in fluoridated than in nonfluoridated communities and that their prevalence at the very mild level may be increasing. In addition to fluoridated drinking water, risk factors for fluorosis include inadvertent ingestion of fluoride toothpaste and the inappropriate use of fluoride supplements. The risk is of aesthetic concern primarily during the period of enamel development of the permanent central incisors, although this largely appears to be a cosmetic rather than a public-health issue. It is concluded that there is a need to co-ordinate studies measuring fluorosis throughout Europe and that development of a standardized photographic method would be useful. Furthermore, the aesthetic importance of fluorosis needs to be determined in more detail in each country in the light of each country's respective risk factors and dental health policies.
在过去50年里,氟化物在预防龋齿方面发挥了关键作用,但在牙齿发育期间过量摄入氟化物可能会导致氟斑牙。在欧洲各地,许多载体过去一直且目前仍在被用于实现最佳的氟化物输送,包括饮用水、牙膏、氟补充剂、盐和牛奶。已经开发并使用了几种描述性和病因学的指数来测量氟斑牙。这个因素,再加上缺乏用于测量氟斑牙的标准化方法,使得不同研究之间难以进行比较,且氟斑牙患病率趋势的评估也不可靠。然而,总体证据似乎表明,与未加氟社区相比,加氟社区中弥漫性釉质混浊更为普遍,而且其非常轻度水平的患病率可能正在上升。除了加氟饮用水外,氟斑牙的风险因素还包括意外摄入含氟牙膏以及不当使用氟补充剂。这种风险主要在恒中切牙釉质发育期间引起美学方面的关注,不过这在很大程度上似乎是一个美容问题而非公共卫生问题。得出的结论是,有必要在整个欧洲协调测量氟斑牙的研究,并且开发一种标准化的摄影方法会很有用。此外,需要根据每个国家各自的风险因素和牙齿健康政策,更详细地确定氟斑牙在美学方面的重要性。