Henderson Max, Tannock Charles
Academic Department of Psychological Medicine, GKT School of Medicine and Institute of Psychiatry, Guys Kings and St. Thomas' Hospital, Weston Education Centre, Cutcombe Road, London SE5 9RJ, UK.
J Psychosom Res. 2004 Feb;56(2):251-4. doi: 10.1016/S0022-3999(03)00571-3.
This study aims to objectively assess the prevalence and nature of personality disorders in depressed and nondepressed chronic fatigue syndrome (CFS) patients and compare this to depressed and healthy control groups.
Sixty-one patients attending a tertiary referral clinic with chronic fatigue syndrome, 40 psychiatric inpatients with depressive disorder and 45 healthy medical students completed the Structured Clinical Interview for DSM-III-R Diagnoses (SCID-II) in addition to providing routine clinical and demographic information.
Thirty-nine percent of the CFS group, 73% of the depressed group and 4% of the healthy group were diagnosed with personality disorders. Cluster C disorders were the most common in both the CFS and depressed group. The depressed CFS patients had more Cluster B personality disorders than nondepressed CFS patients. Overall for CFS patients there was no association between mood state and personality disorder.
High levels of personality disorder are found on objective assessment of CFS patients attending a teaching hospital clinic. This cannot be accounted for by comorbid depression.
本研究旨在客观评估抑郁和非抑郁慢性疲劳综合征(CFS)患者中人格障碍的患病率及性质,并将其与抑郁患者和健康对照组进行比较。
61名到三级转诊诊所就诊的慢性疲劳综合征患者、40名患有抑郁症的精神科住院患者以及45名健康医学生,除了提供常规临床和人口统计学信息外,还完成了《精神疾病诊断与统计手册第三版修订本》(DSM-III-R)结构化临床访谈(SCID-II)。
CFS组中39%、抑郁组中73%以及健康组中4%被诊断患有人格障碍。C组障碍在CFS组和抑郁组中最为常见。抑郁的CFS患者比非抑郁的CFS患者有更多的B组人格障碍。总体而言,CFS患者的情绪状态与人格障碍之间没有关联。
在对一家教学医院诊所的CFS患者进行客观评估时发现了高水平的人格障碍。这不能用共病抑郁症来解释。