Schott K, Bartels M, Heimann H, Buchkremer G
Psychiatrische Universitätsklinik, Tübingen.
Nervenarzt. 1992 Jul;63(7):422-5.
In Tübingen ECT is restricted to severely ill patients who do not respond to other somatic therapies; especially to patients with endogenous depression and pernicious catatonia. Between 1976 and 1990, 45 patients were treated with ECT, of whom 22 suffered from endogenous depression and 10 from pernicious catatonia. Thirteen patients with other diagnoses (schizophrenic and schizoaffective psychoses, borderline schizophrenia and obsessive-compulsive disorder) were treated with ECT for severe depressive states after failure of psychopharmacological therapy. A positive therapeutic response to ECT was observed in 46% of patients with endogenous depression and in all 10 with pernicious catatonia. In the patients with schizophrenia and schizoaffective psychosis, borderline schizophrenia and obsessive-compulsive disorder, an amelioration of the depressive or anxiety syndrome was observed only in individual cases. Side effects of ECT were transit syndromes (20%), reversible amnestic syndromes (20%) and cardiac arrhythmias (6%). According to our results, ECT is highly effective in therapy-resistant endogenous depression and pernicious catatonia, and therefore remains a necessary part of psychiatric therapy.
在图宾根,电休克疗法(ECT)仅限于那些对其他躯体疗法无反应的重症患者;尤其是内源性抑郁症和恶性紧张症患者。1976年至1990年间,45例患者接受了ECT治疗,其中22例患有内源性抑郁症,10例患有恶性紧张症。13例其他诊断(精神分裂症和分裂情感性精神病、边缘型精神分裂症和强迫症)患者在心理药物治疗失败后,因严重抑郁状态接受了ECT治疗。46%的内源性抑郁症患者和所有10例恶性紧张症患者对ECT有积极的治疗反应。在精神分裂症和分裂情感性精神病、边缘型精神分裂症和强迫症患者中,仅个别病例观察到抑郁或焦虑综合征有所改善。ECT的副作用有短暂综合征(20%)、可逆性遗忘综合征(20%)和心律失常(6%)。根据我们的结果,ECT在难治性内源性抑郁症和恶性紧张症的治疗中非常有效,因此仍然是精神科治疗的必要组成部分。