Department of Psychiatry and Biobehavioral Science, UCLA School of Medicine, Los Angeles, CA, USA.
J ECT. 2012 Sep;28(3):e35-6. doi: 10.1097/YCT.0b013e318254c2ea.
Catatonia, associated with a variety of medical and psychiatric conditions such as mood disorders and schizophrenia, is frequently treated with either benzodiazepines or with electroconvulsive therapy (ECT) in treatment-resistant cases. Simultaneous treatment with both is usually avoided. Here, we report a case of the use of the benzodiazepine antagonist flumazenil before ECT to facilitate the simultaneous use of lorazepam and ECT for the treatment of co-occurring catatonia and obsessive-compulsive disorder. Both catatonia and obsessive-compulsive disorder symptoms improved in the patient. Physicians should be aware of flumazenil as a clinical tool for use in treatment-resistant cases.
紧张症与多种医学和精神疾病有关，如心境障碍和精神分裂症，在治疗抵抗的情况下，通常使用苯二氮䓬类药物或电惊厥治疗（ECT）进行治疗。通常避免同时使用这两种方法。在这里，我们报告了一例在 ECT 前使用苯二氮䓬类药物拮抗剂氟马西尼，以促进劳拉西泮和 ECT 的同时使用，治疗同时存在的紧张症和强迫症。患者的紧张症和强迫症症状均得到改善。医生应该意识到氟马西尼是一种用于治疗抵抗病例的临床工具。
