Yardeni Dani, Hirschl Ronald B, Drongowski Robert A, Teitelbaum Daniel H, Geiger James D, Coran Arnold G
Department of Surgery, University of Michigan Health System, Ann Arbor, MI 48109-0245, USA.
J Pediatr Surg. 2004 Mar;39(3):464-9; discussion 464-9. doi: 10.1016/j.jpedsurg.2003.11.020.
BACKGROUND/PURPOSE: Over the last 4 years, the authors changed their management of acute nonperforated appendicitis from emergent surgery within the first 2 to 6 hours of admission to initiation of antibiotic therapy with operation within 24 hours of admission in those seen in the late evening or early morning. They examined, therefore, whether a delay in operation for acute appendicitis would affect outcome measures of patient morbidity and resource use.
The medical records of 126 patients with acute appendicitis occurring between 1998 and 2001 were retrospectively reviewed. Incidence of perforation at surgery, length of stay (LOS), hospital charges, operating time, and complications as a function of duration between emergency room (ER) triage and operation (ER-OR) or admission and operation (Admit-OR) were analyzed by Student's t test, and regression analysis with P less than.05 considered significant.
Thirty-eight children (26%) were operated on within 6 hours of ER triage, whereas the remaining 88 children (74%) were operated on between 6 and 24 hours from ER triage. No significant difference was noted in perforation rate, LOS, costs, or operative time, nor were substantial changes in complications noted between those with an ER-OR < or =6 hours and greater than 6 hours. Likewise, no significant differences in these outcome measures were noted for Admit-OR greater than 6 when compared with < or =6 hours. Only costs with ER-OR greater than 12 hours and LOS with Admit-OR greater than 6 hours were significantly (without Bonferroni correction) different than < or = 6 hours. Multivariable linear regression analysis identified only LOS as a significant predictor of time to OR.
In children with acute appendicitis, delaying surgery until the daytime hours did not significantly affect operating time, perforation rate, or complications. Delayed management allows greater efficiency and effective use of physician and hospital resources, including decreased resident involvement in operations during the night.
背景/目的:在过去4年中,作者将急性非穿孔性阑尾炎的治疗方式从入院后最初2至6小时内进行急诊手术,改为对傍晚或清晨就诊的患者先进行抗生素治疗,并在入院24小时内进行手术。因此,他们研究了急性阑尾炎手术延迟是否会影响患者发病率和资源利用等结果指标。
回顾性分析了1998年至2001年间126例急性阑尾炎患者的病历。通过学生t检验分析手术时的穿孔发生率、住院时间(LOS)、住院费用、手术时间以及作为急诊室(ER)分诊与手术(ER-OR)或入院与手术(Admit-OR)之间时长函数的并发症情况,P值小于0.05的回归分析被认为具有显著性。
38名儿童(26%)在ER分诊后6小时内接受手术,其余88名儿童(74%)在ER分诊后6至24小时内接受手术。穿孔率、LOS、费用或手术时间方面未发现显著差异,ER-OR≤6小时和大于6小时的患者在并发症方面也未出现实质性变化。同样,与Admit-OR≤6小时相比,Admit-OR大于6小时时这些结果指标也未发现显著差异。仅ER-OR大于12小时的费用和Admit-OR大于6小时的LOS与≤6小时时有显著差异(未进行Bonferroni校正)。多变量线性回归分析仅确定LOS是手术时间的显著预测因素。
对于急性阑尾炎儿童患者,将手术推迟至白天时间并未显著影响手术时间、穿孔率或并发症。延迟治疗可提高效率并有效利用医生和医院资源,包括减少夜间住院医生参与手术的情况。