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烧伤创面的延迟一期闭合。

Delayed primary closure of the burn wounds.

作者信息

Prasanna Mita, Mishra Prabodh, Thomas C

机构信息

Department of Plastic Surgery and Burns, Khoula Hospital, Muscat, Sultanate of Oman, Oman.

出版信息

Burns. 2004 Mar;30(2):169-75. doi: 10.1016/j.burns.2003.09.028.

Abstract

'Early closure' of burn wounds by excising the burned tissues and promptly covering it with skin-grafts or its substitutes within first 'five' post-burns day is a standard technique of burn-wound-management in the burn-units of the "developed" world. But lack of education in general, and health-education in particular amongst the common people in the "developing" countries could hinder acceptance of this procedure. Lack of well-trained and motivated burns-surgeons could worsen the situation. The Sultanate of Oman is one of the developing gulf-countries in the middle-east, where at Khoula hospital, the National Burns-Center in the capital city of Muscat, 'early' surgery was introduced in November 1997 to soon become a routine protocol for burn-wound-management. But delay in getting consent for surgery from unwilling patients or in transferring them from the peripheral hospitals were often the reasons for delaying the burn-wound excision and closure 'beyond 6 days to 11th or 12th' day post-burn. Hence, instead of the term "early", the authors prefer to call it "delayed primary" burn-wound closure because, it still offers "primary intention healing" of the burn-wounds. The aim of this article is to analyze retrospectively the results of the "delayed primary" closure of the burn-wounds done in the Khoula Hospital Burns-Unit of the Sultanate of Oman. During a period of 50 months from November 1997 to December 2001, carefully selected 143 patients out of a total of 592 admissions in burns-unit were subjected to burn-wound excision and auto-skin-grafting (STSG), of whom about 87% patients had "delayed primary" and 13% had "early" surgery. There was no mortality or post-operative morbidity in these operated patients. However, due to the non-availability of skin substitutes the excision and auto-grafting could not be done in extensive burns with inadequate skin-donor-area. The maximum percentage of burns treated by delayed primary surgery (DPS) was 50% in children and 55% in adults. Follow-up results were good functionally as well as cosmetically. The authors conclude that "delayed primary" is the second best alternative to the "early" burn-wound excision and closure with similar advantages of reducing risk of septicemia, mortality, and morbidity, hospital stay and cost of treatment. It should be preferred over "secondary" skin-grafting of granulating wounds. Thus, in the developing countries, the indications of delayed primary burn surgery could be (1) patients unstable or unfit for surgery during the first post-burn week; (2) delay in transferring in the patients; (3) delay in getting patient's consent for surgery; (4) very major burns without availability of skin substitutes; and (5) lack of operating time in a busy burns-unit. The contraindications for delayed primary surgery are any sign of invasive sepsis or organ failure.

摘要

在“发达国家”的烧伤治疗单位,通过切除烧伤组织并在烧伤后的头“五天”内迅速用皮肤移植或其替代品覆盖来实现烧伤创面的“早期闭合”,这是一种标准的烧伤创面处理技术。但在“发展中国家”,普通民众普遍缺乏教育,尤其是健康教育,可能会阻碍这种治疗方法的接受。缺乏训练有素且积极性高的烧伤外科医生会使情况恶化。阿曼苏丹国是中东地区发展中的海湾国家之一,在马斯喀特首都的库拉医院(国家烧伤中心),1997年11月引入了“早期”手术,该手术很快成为烧伤创面处理的常规方案。但因不愿手术的患者迟迟不同意手术或从周边医院转运患者延迟,常常导致烧伤创面切除和闭合推迟到烧伤后“6天以上至第11天或12天”。因此,作者更倾向于用“延迟一期”烧伤创面闭合来取代“早期”这一术语,因为它仍能实现烧伤创面的“一期愈合”。本文旨在回顾性分析阿曼苏丹国库拉医院烧伤科进行的烧伤创面“延迟一期”闭合的结果。在1997年11月至2001年12月的50个月期间,从烧伤科总共592例入院患者中精心挑选出143例患者接受烧伤创面切除和自体皮肤移植(自体皮移植),其中约87%的患者接受了“延迟一期”手术,13%的患者接受了“早期”手术。这些接受手术的患者无一例死亡或出现术后并发症。然而,由于没有皮肤替代品,对于供皮区不足的大面积烧伤患者无法进行切除和自体移植。延迟一期手术(DPS)治疗烧伤的最大比例在儿童中为50%,在成人中为55%。随访结果在功能和外观方面都很好。作者得出结论,“延迟一期”是烧伤创面“早期”切除和闭合的次优选择,具有降低败血症风险、死亡率、并发症、住院时间和治疗费用等类似优势。它应优于肉芽创面的“二期”皮肤移植。因此,在发展中国家,延迟一期烧伤手术的适应证可能为:(1)烧伤后第一周内患者病情不稳定或不宜手术;(2)患者转运延迟;(3)获得患者手术同意延迟;(4)大面积严重烧伤且没有皮肤替代品;(5)繁忙的烧伤科缺乏手术时间。延迟一期手术的禁忌证是任何侵袭性败血症或器官衰竭的迹象。

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