肾移植队列中爱泼斯坦-巴尔病毒载量的定量分析及预测移植后淋巴细胞增生性疾病风险的临界值确定。
Quantification of Epstein-Barr viral load and determination of a cut-off value to predict the risk of post-transplant lymphoproliferative disease in a renal transplant cohort.
作者信息
Baiocchi Otávio C G, Colleoni Gisele W B, Caballero Otávia L, Vettore André L, Andrade Ana Lucia S S, Pestana José O M
出版信息
Haematologica. 2004 Mar;89(3):366-8.
PMID:15020282
Abstract
Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening Epstein-Barr virus (EBV)-driven B-cell malignancy occurring in 1 to 3% of renal transplant patients. Recently, EBV DNA quantification has become a useful tool for identifying patients at risk of developing PTLD. However, studies on EBV load differ in design, methodology and type of patients.
摘要
移植后淋巴细胞增生性疾病（PTLD）是一种由爱泼斯坦-巴尔病毒（EBV）驱动的、危及生命的B细胞恶性肿瘤，在1%至3%的肾移植患者中发生。最近，EBV DNA定量已成为识别有发生PTLD风险患者的有用工具。然而，关于EBV载量的研究在设计、方法和患者类型方面存在差异。
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