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Allogeneic bone marrow transplantation with non-T-cell-depleted marrow from two HLA-antigen-mismatched related donors.

作者信息

Ogawa Hiroyasu, Ikegame Kazuhiro, Kawakami Manabu, Taniguchi Yuki, Oka Yoshihiro, Kawase Ichiro

出版信息

Haematologica. 2004 Mar;89(3):373-5.

PMID:15020286
Abstract

Allogeneic BMT from 2 antigen-mismatched donors has been difficult to perform without T-cell depletion. Seven patients with advanced-stage hematologic malignancies underwent BMT with intensified graft-versus-host disease prophylaxis consisting of tacrolimus, methotrexate, and methylprednisolone. No rejection or acute GVHD >or= grade III was observed. This preliminary result is very promising.

摘要

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