Henry R J, Primosch R E, Courts F J
University of Florida College of Dentistry, Gainesville.
Pediatr Dent. 1992 Jan-Feb;14(1):19-25.
This prospective study of 36 children, ages 44-93 months, receiving nitrous oxide-oxygen under standardized conditions during routine dental procedures was conducted to determine what influence eight selected dental procedures and three patient behaviors had on ambient nitrous oxide (N2O) levels in the dentist's breathing zone. Half the children received nitrous oxide-oxygen via a scavenging nasal mask. An infrared spectrophotometer analyzed the ambient N2O level continuously throughout the procedure and the time-weighted average (TWA) for consecutive 15-sec intervals was recorded by a microprocessor. A video camera was used to synchronize the coded dental procedures and patient behaviors to the TWA ambient N2O levels recorded. The results demonstrated that scavenging significantly reduced the dentist's exposure to ambient N2O (P less than 0.05, nonscavenged mean = 284.7 ppm; scavenged mean = 36.6 ppm), but the mean TWA N2O concentration remained significantly higher, P less than 0.05, than the 25-ppm level recommended by the National Institute for Occupational Safety and Health (NIOSH). Supplemental oral evacuation was the only dental procedure capable of reducing ambient N2O to below NIOSH's recommendation when scavenging was employed. The administration of local anesthesia consistently created a significant increase in ambient N2O levels. Patient behaviors of talking, crying, and movement also resulted in significant increases from baseline ambient N2O levels.
本前瞻性研究纳入了36名年龄在44至93个月的儿童,他们在常规牙科手术中于标准化条件下接受氧化亚氮-氧气吸入。该研究旨在确定八项选定的牙科手术和三种患者行为对牙医呼吸区内环境氧化亚氮(N2O)水平有何影响。一半的儿童通过带有清除装置的鼻罩接受氧化亚氮-氧气吸入。在整个手术过程中,用红外分光光度计持续分析环境N2O水平,微处理器记录连续15秒间隔的时间加权平均值(TWA)。使用摄像机将编码后的牙科手术和患者行为与记录的TWA环境N2O水平同步。结果表明,清除装置显著降低了牙医对环境N2O的暴露(P小于0.05,未使用清除装置时的平均值 = 284.7 ppm;使用清除装置时的平均值 = 36.6 ppm),但TWA N2O平均浓度仍显著高于美国国家职业安全与健康研究所(NIOSH)推荐的25 ppm水平(P小于0.05)。当使用清除装置时,补充口腔抽吸是唯一能够将环境N2O降低至NIOSH推荐水平以下的牙科手术。局部麻醉的施用始终会使环境N2O水平显著升高。患者说话、哭泣和移动的行为也会导致环境N2O水平较基线显著升高。