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The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome.

作者信息

Radstake Timothy R D J, Franke Barbara, Hanssen Suzanne, Netea Mihai G, Welsing Paco, Barrera Pilar, Joosten Leo A B, van Riel Piet L C M, van den Berg Wim B

机构信息

University Medical Center Nijmegen, Nijmegen, The Netherlands.

出版信息

Arthritis Rheum. 2004 Mar;50(3):999-1001. doi: 10.1002/art.20114.

DOI:10.1002/art.20114
PMID:15022344
Abstract
摘要

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The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome.Toll样受体4 Asp299Gly功能变体与类风湿性关节炎疾病易感性降低相关，但不影响疾病严重程度和/或预后。
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