卡氏肺孢子虫肺炎及其与艾滋病中其他机会性感染的关联——5例尸检报告

Pneumocystis carinii pneumonia and its association with other opportunistic infections in AIDS--an autopsy report of five cases.

作者信息

Deshmukh Sanjay D, Ghaisas Manali V, Rane Sharada R, Bapat Vishnuprasad M

机构信息

Department of Pathology, B.J. Medical College and Sassoon General Hospitals, Pune 411001.

出版信息

Indian J Pathol Microbiol. 2003 Apr;46(2):207-11.

PMID:15022911

Abstract

Pneumocystis carinii pneumonia (PCP) has been reported as one of the opportunistic pathogens in AIDS. The significance of this pathogen in AIDS is well established so that, the diagnosis of PCP in an adult simultaneously establishes the diagnosis of AIDS. This point is well emphasised in the CDC case definition of AIDS. In western literature, the occurrence of PCP in AIDS is widely reported. However, in Indian literature only sporadic case reports have been documented. This study reports 5 cases of PCP encountered amongst 34 AIDS-autopsies studied. PCP alone was present in 2 cases. It is worth noting that it was simultaneously associated with cryptococcosis, tuberculosis and CMV in 3 remaining cases, highlighting the need for extensive investigations even after establishing the diagnosis of PCP in a known full blown AIDS patient.

摘要

卡氏肺孢子虫肺炎（PCP）已被报道为艾滋病患者的机会性病原体之一。这种病原体在艾滋病中的重要性已得到充分证实，以至于在成人中诊断出PCP同时也就确立了艾滋病的诊断。美国疾病控制与预防中心（CDC）的艾滋病病例定义中很好地强调了这一点。在西方文献中，艾滋病患者中PCP的发生情况有广泛报道。然而，在印度文献中仅有零星的病例报告。本研究报告了在34例艾滋病尸检病例中发现的5例PCP。仅PCP存在的有2例。值得注意的是，在其余3例中它同时与隐球菌病、结核病和巨细胞病毒（CMV）相关，这突出表明即使在已知的典型艾滋病患者中确诊PCP后仍需要进行广泛的检查。