Cole Jason H, Sperling Laurence S
Emory Center for Outcomes Research, 1256 Briarcliff Road, Suite 1-North, Atlanta, GA 30306, USA.
Curr Atheroscler Rep. 2004 Mar;6(2):121-5. doi: 10.1007/s11883-004-0100-z.
Coronary artery disease (CAD) that becomes manifest in young adults can have devastating consequences. Additionally, the study of young patients with CAD may provide insight into the genetic basis of coronary disease. Over the past few years, our understanding of risk factors in this population has been expanded to include social, environmental, and emotional factors. The identification of genetic markers for disease is just beginning. Also, it has recently been shown that CAD in young adults has a poor long-term prognosis, meaning that clinicians caring for these patients must be aggressive in risk factor control.
在年轻成年人中显现的冠状动脉疾病(CAD)可能会产生毁灭性后果。此外,对年轻CAD患者的研究可能会为冠状动脉疾病的遗传基础提供见解。在过去几年中,我们对这一人群风险因素的认识已扩展到包括社会、环境和情感因素。疾病遗传标记的识别才刚刚开始。而且,最近有研究表明,年轻成年人的CAD长期预后较差,这意味着照料这些患者的临床医生必须积极控制风险因素。