Pradhan Pramila
Department of Obstetrics and Gynecology, Nepal Medical College Teaching Hospital, Jorpati, Kathmandu, Nepal.
Nepal Med Coll J. 2003 Dec;5(2):82-6.
This study was undertaken to evaluate the prevalence of Cervical precancerous and Cancer pick up by single pap smear test. A prospective study of pap smear test of three years duration 2000-2002 in Obstetrics and Gynecology department, NMCTH, Kathmandu. A total 800 cases were included Maximum number of patients are in the age group of active reproductive period (21-40 yr) with higher rate of an abnormal smear in Brahmin ethnic group. The main complaints are of lower abdominal pain and white discharge per vaginum. The main cervical pathology is cervicitis, cervical erosion and cervical hypertrophied with bleeding on touch. 4.8% of the patients had abnormal smear including three patients with invasive cervical squamous cell carcinoma detected on pap smear test. This study shows that routine pap smear screening in patients attending gynecological OPD is the good method of detecting precancerous cervical intraepithelial neoplasia (CIN) lesion and early cervical cancer, which would go undiagnosed otherwise with worst morbidity and mortality. We should try to cover 100% screening if possible in an institution at least to begin with.
本研究旨在评估单次巴氏涂片检查对宫颈癌前病变和癌症的检出率。对加德满都NMCTH妇产科2000年至2002年为期三年的巴氏涂片检查进行前瞻性研究。共纳入800例病例，最大数量的患者处于活跃生育期（21 - 40岁），婆罗门族裔涂片异常率较高。主要症状为下腹痛和阴道白带增多。主要宫颈病理表现为宫颈炎、宫颈糜烂和宫颈肥大伴触血。4.8%的患者涂片异常，其中包括3例在巴氏涂片检查中检测出的浸润性宫颈鳞状细胞癌患者。本研究表明，对妇科门诊患者进行常规巴氏涂片筛查是检测宫颈癌前上皮内瘤变（CIN）病变和早期宫颈癌的良好方法，否则这些病变将无法被诊断，从而导致更高的发病率和死亡率。如果可能，我们应至少在一个机构中首先尝试实现100%的筛查覆盖率。
