偏头痛的机制与管理。

Migraine mechanism and management.

作者信息

Spierings Egilius L

机构信息

Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

出版信息

Otolaryngol Clin North Am. 2003 Dec;36(6):1063-78, v-vi. doi: 10.1016/s0030-6665(03)00129-4.

DOI:10.1016/s0030-6665(03)00129-4

PMID:15025007

Abstract

Migraine affects an estimated 10% to 15% of the population with greater or lesser regularity and throughout much of their lifetime. It causes disability, be it often temporary, and strains personal relationships and professional development. Little is known about it scientifically, and its treatment remains mostly empirical. This article describes the pathogenesis of migraine, as well as its management in terms of abortive and preventive treatment.

摘要

据估计，偏头痛在大约10%至15%的人群中发作，发作频率或高或低，且贯穿他们一生的大部分时间。它会导致残疾，尽管通常是暂时的，还会影响人际关系和职业发展。从科学角度对其了解甚少，其治疗大多仍基于经验。本文描述了偏头痛的发病机制，以及发作期和预防性治疗方面的管理方法。