Nicholas W C, Cranston P E, Weems W L
Department of Medicine, University of Mississippi Medical Center, Jackson 39216-4505.
South Med J. 1992 Aug;85(8):853-6.
A 26-year-old woman with regularly documented normal blood pressure had sudden onset of severe hypertension. Investigation revealed an intrarenal artery aneurysm involving the upper pole of the left kidney, as well as elevated levels of both renin and aldosterone. With ACE inhibitor therapy, blood pressure promptly returned to normal, and subsequent surgical removal of the upper pole of the involved kidney has resulted in normal blood pressure for 9 months of follow-up. Although uncommon, intrarenal aneurysms may lead to severe renal vascular hypertension that is relieved by surgery. This definitive procedure may not take place if one is not aware of the excellent response to ACE inhibitors in this situation.
一名26岁女性,血压一直正常且有记录,却突然出现严重高血压。检查发现左肾上极有一个肾内动脉动脉瘤,同时肾素和醛固酮水平升高。采用血管紧张素转换酶抑制剂治疗后,血压迅速恢复正常,随后手术切除患肾的上极,随访9个月血压一直正常。肾内动脉瘤虽不常见,但可能导致严重的肾血管性高血压,手术可缓解。如果不了解这种情况下血管紧张素转换酶抑制剂的良好疗效,可能无法进行这种确定性手术。